Influence of ginger root extract supplementation on the microbiota-gut-brain axis in individuals with sciatica: Study protocol for a double-blind, placebo-controlled randomized trial.
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| Title: | Influence of ginger root extract supplementation on the microbiota-gut-brain axis in individuals with sciatica: Study protocol for a double-blind, placebo-controlled randomized trial. |
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| Authors: | Shen CL; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: leslie.shen@ttuhsc.edu., Elmassry MM; Department of Molecular Biology, Princeton University, Princeton, NJ 08540, USA. Electronic address: elmassry@princeton.edu., Kahathuduwa C; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Neurology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: chanaka.kahathuduwa@ttuhsc.edu., Lee J; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Educational Psychology and Leadership, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: jaehoon.lee@ttu.edu., Day MR; Department of Anesthesiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: miles.day@ttuhsc.edu., Edwards DS; Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: david.s.edwards@ttuhsc.edu., Parmar H; Texas Tech Neuroimaging Institute, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: harshit.parmar@ttu.edu., Wager TD; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA. Electronic address: tor.d.wager@dartmouth.edu., Liu X; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: xiaobo.liu@ttuhsc.edu., Baccus M; Clinical Research Institute, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: melanie.baccus@ttuhsc.edu., Hamood A; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: abdul.hamood@ttuhsc.edu., Neugebauer V; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: volker.neugebauer@ttuhsc.edu. |
| Source: | Clinical nutrition ESPEN [Clin Nutr ESPEN] 2026 Jun; Vol. 73, pp. 103117. Date of Electronic Publication: 2026 Mar 12. |
| Publication Type: | Clinical Trial Protocol; Journal Article |
| Journal Info: | Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41831719 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Influence of ginger root extract supplementation on the microbiota-gut-brain axis in individuals with sciatica: Study protocol for a double-blind, placebo-controlled randomized trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Shen+CL%22">Shen CL</searchLink>; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: leslie.shen@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Elmassry+MM%22">Elmassry MM</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ 08540, USA. Electronic address: elmassry@princeton.edu.<br /><searchLink fieldCode="AU" term="%22Kahathuduwa+C%22">Kahathuduwa C</searchLink>; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Neurology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: chanaka.kahathuduwa@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Educational Psychology and Leadership, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: jaehoon.lee@ttu.edu.<br /><searchLink fieldCode="AU" term="%22Day+MR%22">Day MR</searchLink>; Department of Anesthesiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: miles.day@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Edwards+DS%22">Edwards DS</searchLink>; Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: david.s.edwards@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Parmar+H%22">Parmar H</searchLink>; Texas Tech Neuroimaging Institute, Texas Tech University, Lubbock, TX, 79409, USA. Electronic address: harshit.parmar@ttu.edu.<br /><searchLink fieldCode="AU" term="%22Wager+TD%22">Wager TD</searchLink>; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA. Electronic address: tor.d.wager@dartmouth.edu.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: xiaobo.liu@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Baccus+M%22">Baccus M</searchLink>; Clinical Research Institute, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: melanie.baccus@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Hamood+A%22">Hamood A</searchLink>; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: abdul.hamood@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Neugebauer+V%22">Neugebauer V</searchLink>; Center of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: volker.neugebauer@ttuhsc.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101654592%22">Clinical nutrition ESPEN</searchLink> [Clin Nutr ESPEN] 2026 Jun; Vol. 73, pp. 103117. <i>Date of Electronic Publication: </i>2026 Mar 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial Protocol; Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101654592 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2405-4577 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224054577%22">24054577 </searchLink><i>NLM ISO Abbreviation: </i>Clin Nutr ESPEN <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41831719 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.clnesp.2026.103117 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 103117 Titles: – TitleFull: Influence of ginger root extract supplementation on the microbiota-gut-brain axis in individuals with sciatica: Study protocol for a double-blind, placebo-controlled randomized trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shen CL – PersonEntity: Name: NameFull: Elmassry MM – PersonEntity: Name: NameFull: Kahathuduwa C – PersonEntity: Name: NameFull: Lee J – PersonEntity: Name: NameFull: Day MR – PersonEntity: Name: NameFull: Edwards DS – PersonEntity: Name: NameFull: Parmar H – PersonEntity: Name: NameFull: Wager TD – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Baccus M – PersonEntity: Name: NameFull: Hamood A – PersonEntity: Name: NameFull: Neugebauer V IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2405-4577 Numbering: – Type: volume Value: 73 Titles: – TitleFull: Clinical nutrition ESPEN Type: main |
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