Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.

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Title: Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.
Authors: Kraemer BR; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Heo G; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Chen CH; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Mochly-Rosen D; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA. mochly@stanford.edu.
Source: Communications biology [Commun Biol] 2026 Mar 14; Vol. 9 (1). Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2399-3642
DOI:10.1038/s42003-026-09845-y