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Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.

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Title: Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.
Authors: Kraemer BR; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Heo G; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Chen CH; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA., Mochly-Rosen D; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA. mochly@stanford.edu.
Source: Communications biology [Commun Biol] 2026 Mar 14; Vol. 9 (1). Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.
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  Data: <searchLink fieldCode="AU" term="%22Kraemer+BR%22">Kraemer BR</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Heo+G%22">Heo G</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mochly-Rosen+D%22">Mochly-Rosen D</searchLink>; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA. mochly@stanford.edu.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2026 Mar 14; Vol. 9 (1). <i>Date of Electronic Publication: </i>2026 Mar 14.
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        Value: 10.1038/s42003-026-09845-y
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        Text: English
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      – TitleFull: Increased susceptibility to 4-HNE-induced toxicity and impaired development in a model of ALDH4A1-deficient pediatric epilepsy carrying the S352L variant.
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              Text: 2026 Mar 14
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              Y: 2026
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