Measuring blood-brain barrier dysfunction: a critical appraisal of fluid biomarkers, in vitro models, in vivo imaging, and post-mortem approaches.

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Title: Measuring blood-brain barrier dysfunction: a critical appraisal of fluid biomarkers, in vitro models, in vivo imaging, and post-mortem approaches.
Authors: van der Panne SA; Department of Biomedical Engineering and Physics, Amsterdam University Medical Centre, Location AMC, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Amsterdam University Medical Centre, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, Amsterdam, The Netherland., Durrant H; C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands., Heuer JF; Amsterdam Neuroscience, Amsterdam University Medical Centre, Amsterdam, The Netherlands.; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Centre, Location VUmc, Amsterdam, The Netherlands., Kancheva I; C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands., Stellingwerf A; Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Alzheimer Centre, Radboud University Medical Centre, Nijmegen, The Netherlands., Verkaar LTKM; Department of Geriatric Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands., Verstappen D; Department of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.; Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands., Mossel P; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands., Backes WH; Department of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.; Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands., Bakker ENTP; Department of Biomedical Engineering and Physics, Amsterdam University Medical Centre, Location AMC, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, Amsterdam, The Netherland., Claassen JAHR; Department of Geriatric Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Verbeek MM; Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Alzheimer Centre, Radboud University Medical Centre, Nijmegen, The Netherlands.; Department of Human Genetics, Radboud University Medical Centre, Nijmegen, The Netherlands., van der Weerd L; C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands., van Osch MJP; C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands., de Vries HE; Amsterdam Neuroscience, Amsterdam University Medical Centre, Amsterdam, The Netherlands.; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Centre, Location VUmc, Amsterdam, The Netherlands.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Mar; Vol. 22 (3), pp. e71263.
Publication Type: Journal Article; Review
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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