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Testing the performance of polygenic scores for multiple traits to explain cerebral palsy in two independent cohorts.

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Title: Testing the performance of polygenic scores for multiple traits to explain cerebral palsy in two independent cohorts.
Authors: Thomas JT; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia., Berry ASF; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA., Oetjens MT; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA., Berry JG; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia., MacLennan AH; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia., Gordon SD; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia., Hale AT; Department of Neurosurgery, The University of Alabama at Birmingham, Birmingham, AL, USA; Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Olsen CM; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia., Whiteman DC; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia., Torene RI; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA., Ledbetter DH; Institute for Pediatric Rare Diseases, College of Medicine, Florida State University, Tallahassee, FL, USA., Martin NG; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia., van Eyk CL; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia., Gecz J; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Myers SM; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA., Mitchell BL; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia., Corbett MA; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia. Electronic address: mark.corbett@adelaide.edu.au.
Source: EBioMedicine [EBioMedicine] 2026 Apr; Vol. 126, pp. 106208. Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Testing the performance of polygenic scores for multiple traits to explain cerebral palsy in two independent cohorts.
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  Data: <searchLink fieldCode="AU" term="%22Thomas+JT%22">Thomas JT</searchLink>; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Berry+ASF%22">Berry ASF</searchLink>; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Oetjens+MT%22">Oetjens MT</searchLink>; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Berry+JG%22">Berry JG</searchLink>; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22MacLennan+AH%22">MacLennan AH</searchLink>; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Gordon+SD%22">Gordon SD</searchLink>; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Hale+AT%22">Hale AT</searchLink>; Department of Neurosurgery, The University of Alabama at Birmingham, Birmingham, AL, USA; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Olsen+CM%22">Olsen CM</searchLink>; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Whiteman+DC%22">Whiteman DC</searchLink>; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Torene+RI%22">Torene RI</searchLink>; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ledbetter+DH%22">Ledbetter DH</searchLink>; Institute for Pediatric Rare Diseases, College of Medicine, Florida State University, Tallahassee, FL, USA.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22van+Eyk+CL%22">van Eyk CL</searchLink>; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Gecz+J%22">Gecz J</searchLink>; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Myers+SM%22">Myers SM</searchLink>; Department of Developmental Medicine, Geisinger College of Health Sciences, Lewisburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+BL%22">Mitchell BL</searchLink>; Brain and Mental Health Program, QIMR Berghofer, Brisbane, QLD, Australia; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Corbett+MA%22">Corbett MA</searchLink>; School of Medicine and Robinson Research Institute, College of Health, Adelaide University, Adelaide, SA, Australia. Electronic address: mark.corbett@adelaide.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2026 Apr; Vol. 126, pp. 106208. <i>Date of Electronic Publication: </i>2026 Mar 14.
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