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Enhanced Mitochondrial Mrs2-Mg2+ Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats.

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Title: Enhanced Mitochondrial Mrs2-Mg2+ Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats.
Authors: Chen RN; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Weng XQ; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Yan Y; Department of Cardiology (Y.Y.), The First Affiliated Hospital of Fujian Medical University, Fuzhou, China., Chen QY; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Lin YC; Department of Vascular Surgery (Y.-C.L.), The First Affiliated Hospital of Fujian Medical University, Fuzhou, China., Liu L; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Zhuang XL; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Gui LX; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Sham JSK; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (J.S.K.S.)., Lin MJ; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.)., Lin DC; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).; Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China (D.-C.L.).
Source: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2026 Jun; Vol. 83 (6), pp. e25866. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE
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  Data: Enhanced Mitochondrial Mrs2-Mg<superscript>2+</superscript> Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats.
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  Data: <searchLink fieldCode="AU" term="%22Chen+RN%22">Chen RN</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Weng+XQ%22">Weng XQ</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Department of Cardiology (Y.Y.), The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+QY%22">Chen QY</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Lin+YC%22">Lin YC</searchLink>; Department of Vascular Surgery (Y.-C.L.), The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Zhuang+XL%22">Zhuang XL</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Gui+LX%22">Gui LX</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Sham+JSK%22">Sham JSK</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (J.S.K.S.).<br /><searchLink fieldCode="AU" term="%22Lin+MJ%22">Lin MJ</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).<br /><searchLink fieldCode="AU" term="%22Lin+DC%22">Lin DC</searchLink>; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China (R.-N.C., X.-Q.W., Q.-Y.C., L.L., X.-L.Z., L.-X.G., M.-J.L., D.-C.L.).; Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China (D.-C.L.).
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  Data: <searchLink fieldCode="JN" term="%227906255%22">Hypertension (Dallas, Tex. : 1979)</searchLink> [Hypertension] 2026 Jun; Vol. 83 (6), pp. e25866. <i>Date of Electronic Publication: </i>2026 Mar 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott%2C+Williams+%26+Wilkins%22">Lippincott, Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7906255 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1524-4563 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220194911X%22">0194911X </searchLink><i>NLM ISO Abbreviation: </i>Hypertension <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41834713
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1161/HYPERTENSIONAHA.126.25866
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      – Code: eng
        Text: English
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        StartPage: e25866
    Titles:
      – TitleFull: Enhanced Mitochondrial Mrs2-Mg2+ Signaling Drives Mitochondrial Dysfunction in Pulmonary Arterial Hypertension Rats.
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            NameFull: Chen RN
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            – D: 01
              M: 06
              Text: 2026 Jun
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              Y: 2026
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              Value: 6
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            – TitleFull: Hypertension (Dallas, Tex. : 1979)
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