Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.

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Bibliographic Details
Title: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.
Authors: Hu Z; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Yin Z; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany., Lu G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., Luo Q; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., He X; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Zhan L; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Goldfuss B; Department for Chemistry, Institute of Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany., Xu J; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Bian G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Dickschat JS; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2026 Mar 25; Vol. 148 (11), pp. 12377-12386. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-5126
DOI:10.1021/jacs.6c02649