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Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.

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Title: Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.
Authors: Jamadagni P; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Dai Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Weinschutz Mendes H; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Pruitt A; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510., Khan S; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Yang L; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Huang TC; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Huang X; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Deans PJM; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Balafkan N; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen 7804, Norway., Zhao D; Department of Genetics, Yale School of Medicine, New Haven, CT 06510., Xu G; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Li N; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China., Wu W; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Fitzpatrick SE; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510.; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510., Neelakantan U; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Chen T; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Szialta C; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Jin DS; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510.; Department of Neurology, Yale School of Medicine, New Haven, CT 06510., Lacadie CM; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510.; Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510., Umlauf S; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510., Papademetris X; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510.; Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510., Surovtseva YV; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510., Brennand KJ; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Department of Genetics, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510., Wang Z; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510., Hoffman EJ; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 24; Vol. 123 (12), pp. e2518846123. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.
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  Data: <searchLink fieldCode="AU" term="%22Jamadagni+P%22">Jamadagni P</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Dai+Y%22">Dai Y</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Weinschutz+Mendes+H%22">Weinschutz Mendes H</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Pruitt+A%22">Pruitt A</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Khan+S%22">Khan S</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Huang+TC%22">Huang TC</searchLink>; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Deans+PJM%22">Deans PJM</searchLink>; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Balafkan+N%22">Balafkan N</searchLink>; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen 7804, Norway.<br /><searchLink fieldCode="AU" term="%22Zhao+D%22">Zhao D</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Xu+G%22">Xu G</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+SE%22">Fitzpatrick SE</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; 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Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Umlauf+S%22">Umlauf S</searchLink>; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Papademetris+X%22">Papademetris X</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510.; Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Surovtseva+YV%22">Surovtseva YV</searchLink>; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Brennand+KJ%22">Brennand KJ</searchLink>; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Department of Genetics, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510.<br /><searchLink fieldCode="AU" term="%22Hoffman+EJ%22">Hoffman EJ</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510.
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