Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.

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Title: Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.
Authors: Jamadagni P; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Dai Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Weinschutz Mendes H; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Pruitt A; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510., Khan S; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Yang L; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Huang TC; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Huang X; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Deans PJM; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511., Balafkan N; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen 7804, Norway., Zhao D; Department of Genetics, Yale School of Medicine, New Haven, CT 06510., Xu G; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Li N; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China., Wu W; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510., Fitzpatrick SE; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510.; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510., Neelakantan U; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Chen T; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Szialta C; Child Study Center, Yale School of Medicine, New Haven, CT 06510., Jin DS; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510.; Department of Neurology, Yale School of Medicine, New Haven, CT 06510., Lacadie CM; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510.; Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510., Umlauf S; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510., Papademetris X; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510.; Yale Biomedical Imaging Institute, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510., Surovtseva YV; Yale Center for Molecular Discovery, Yale School of Medicine, New Haven, CT 06510., Brennand KJ; Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06511.; Department of Genetics, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510., Wang Z; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT 06510., Hoffman EJ; Child Study Center, Yale School of Medicine, New Haven, CT 06510.; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 24; Vol. 123 (12), pp. e2518846123. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2518846123