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CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis.

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Title: CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis.
Authors: Almeida-Santos G; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: yqv6ae@virginia.edu., Santiago-Carvalho I; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Department of Immunology, Mayo Clinic, Scottsdale, AZ, USA., Almeida FM; Laboratório de Biologia do Reconhecer, State University of North Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil., Barbosa Bomfim CC; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, Toulouse, France., Santos E Silva JC; USP, Faculdade de Ciências Farmacêuticas (FCF), Departamento de Análises Clínicas e Toxicológicas, São Paulo, Brazil., Cantarini DG; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil., Silva CR; Instituto de Pesquisas Energéticas e Nucleares (IPEN), Brazil., Ribeiro MS; Instituto de Pesquisas Energéticas e Nucleares (IPEN), Brazil., do Nascimento RS; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil., de Gois Macedo B; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Department of Immunology, Mayo Clinic, Scottsdale, AZ, USA., Lisboa Raeder PH; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil., Teixeira-Xavier Junior J; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil., Alvarez JM; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil., Hirata MH; USP, Faculdade de Ciências Farmacêuticas (FCF), Departamento de Análises Clínicas e Toxicológicas, São Paulo, Brazil., Coutinho-Silva R; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Robson SC; Harvard Medical School, Boston, MA, USA; Beth Israel Deaconess Medical Center, Boston, MA, USA., Amaral EP; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Lasunskaia E; Laboratório de Biologia do Reconhecer, State University of North Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil., D'Império Lima MR; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil. Electronic address: relima@usp.br.
Source: Mucosal immunology [Mucosal Immunol] 2026 Jun; Vol. 19 (3), pp. 100333. Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis.
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  Data: <searchLink fieldCode="AU" term="%22Almeida-Santos+G%22">Almeida-Santos G</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: yqv6ae@virginia.edu.<br /><searchLink fieldCode="AU" term="%22Santiago-Carvalho+I%22">Santiago-Carvalho I</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Department of Immunology, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Almeida+FM%22">Almeida FM</searchLink>; Laboratório de Biologia do Reconhecer, State University of North Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Barbosa+Bomfim+CC%22">Barbosa Bomfim CC</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Santos+E+Silva+JC%22">Santos E Silva JC</searchLink>; USP, Faculdade de Ciências Farmacêuticas (FCF), Departamento de Análises Clínicas e Toxicológicas, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Cantarini+DG%22">Cantarini DG</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+CR%22">Silva CR</searchLink>; Instituto de Pesquisas Energéticas e Nucleares (IPEN), Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+MS%22">Ribeiro MS</searchLink>; Instituto de Pesquisas Energéticas e Nucleares (IPEN), Brazil.<br /><searchLink fieldCode="AU" term="%22do+Nascimento+RS%22">do Nascimento RS</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Gois+Macedo+B%22">de Gois Macedo B</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil; Department of Immunology, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Lisboa+Raeder+PH%22">Lisboa Raeder PH</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Teixeira-Xavier+Junior+J%22">Teixeira-Xavier Junior J</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Alvarez+JM%22">Alvarez JM</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Hirata+MH%22">Hirata MH</searchLink>; USP, Faculdade de Ciências Farmacêuticas (FCF), Departamento de Análises Clínicas e Toxicológicas, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Coutinho-Silva+R%22">Coutinho-Silva R</searchLink>; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Robson+SC%22">Robson SC</searchLink>; Harvard Medical School, Boston, MA, USA; Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amaral+EP%22">Amaral EP</searchLink>; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lasunskaia+E%22">Lasunskaia E</searchLink>; Laboratório de Biologia do Reconhecer, State University of North Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22D'Império+Lima+MR%22">D'Império Lima MR</searchLink>; Universidade de São Paulo (USP), Instituto de Ciências Biomédicas (ICB), Departamento de Imunologia, São Paulo, Brazil. Electronic address: relima@usp.br.
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  Data: <searchLink fieldCode="JN" term="%22101299742%22">Mucosal immunology</searchLink> [Mucosal Immunol] 2026 Jun; Vol. 19 (3), pp. 100333. <i>Date of Electronic Publication: </i>2026 Mar 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101299742 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1935-3456 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219330219%22">19330219 </searchLink><i>NLM ISO Abbreviation: </i>Mucosal Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.mucimm.2026.03.007
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        Text: English
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              Text: 2026 Jun
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