Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex.

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Title: Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex.
Authors: Meng J; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Chen C; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China., Zhu Z; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China., Sun Y; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Huang Y; Lingang Laboratory, Shanghai, China.; School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China., Hu K; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Fu J; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Wu L; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Li L; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Bai Y; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Fei T; School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China., Liu Z; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China., Li C; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Shen Z; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China., Liu L; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China., Li C; Lingang Laboratory, Shanghai, China., Song T; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Liu C; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Poo M; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China., Liu S; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China. liushiping@genomics.cn.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China. liushiping@genomics.cn., Lei Y; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China. leiying1@genomics.cn.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China. leiying1@genomics.cn.; Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering Hainan University, Sanya, China. leiying1@genomics.cn., Sun Y; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China. ydsun@ion.ac.cn.; Shanghai Key Laboratory of Precision Gene Editing and Clinical Translation, Shanghai, China. ydsun@ion.ac.cn.
Source: Nature communications [Nat Commun] 2026 Mar 17; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex.
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  Data: <searchLink fieldCode="AU" term="%22Meng+J%22">Meng J</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Lingang Laboratory, Shanghai, China.; School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hu+K%22">Hu K</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fu+J%22">Fu J</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fei+T%22">Fei T</searchLink>; School of Life Sciences and Technology, ShanghaiTech University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shen+Z%22">Shen Z</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Lingang Laboratory, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Song+T%22">Song T</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Poo+M%22">Poo M</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China. liushiping@genomics.cn.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China. liushiping@genomics.cn.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China. leiying1@genomics.cn.; Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research, Hangzhou, 310030, China. leiying1@genomics.cn.; Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering Hainan University, Sanya, China. leiying1@genomics.cn.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Genetic Evolution & Animal Models, Chinese Academy of Sciences, Shanghai, China. ydsun@ion.ac.cn.; Shanghai Key Laboratory of Precision Gene Editing and Clinical Translation, Shanghai, China. ydsun@ion.ac.cn.
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