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Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interface.

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Title: Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interface.
Authors: Turner DL; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Baric H; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia., Patatsos K; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia., Amoozadeh S; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., See M; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia., Strumila KA; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Murphy JT; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Wiyana JJ; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Gubbels L; Murdoch Children's Research Institute, Melbourne, Victoria, Australia., Ng ES; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Elefanty AG; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Neeland MR; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Shanthikumar S; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.; Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, Australia., Londrigan SL; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Ramialison M; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Rossello FJ; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Stanley EG; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Werder RB; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.
Source: JCI insight [JCI Insight] 2026 Mar 17; Vol. 11 (9). Date of Electronic Publication: 2026 Mar 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interface.
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  Data: <searchLink fieldCode="AU" term="%22Turner+DL%22">Turner DL</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Baric+H%22">Baric H</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Patatsos+K%22">Patatsos K</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Amoozadeh+S%22">Amoozadeh S</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22See+M%22">See M</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Strumila+KA%22">Strumila KA</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Murphy+JT%22">Murphy JT</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Wiyana+JJ%22">Wiyana JJ</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Gubbels+L%22">Gubbels L</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ng+ES%22">Ng ES</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Elefanty+AG%22">Elefanty AG</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Neeland+MR%22">Neeland MR</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Shanthikumar+S%22">Shanthikumar S</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.; Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Londrigan+SL%22">Londrigan SL</searchLink>; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Ramialison+M%22">Ramialison M</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Rossello+FJ%22">Rossello FJ</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Stanley+EG%22">Stanley EG</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Werder+RB%22">Werder RB</searchLink>; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Novo Nordisk Foundation Centre for Stem Cell Medicine, reNEW Melbourne, Melbourne, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2026 Mar 17; Vol. 11 (9). <i>Date of Electronic Publication: </i>2026 Mar 17 (<i>Print Publication: </i>2026).
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