Phase 2 study of azacitidine plus pembrolizumab as second-line treatment in patients with locally advanced or metastatic pancreatic ductal adenocarcinoma.

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Title: Phase 2 study of azacitidine plus pembrolizumab as second-line treatment in patients with locally advanced or metastatic pancreatic ductal adenocarcinoma.
Authors: Safyan RA; University of Washington School of Medicine, Seattle, WA, 98195, United States.; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States., White RA; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States., Gonda TA; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States., Lee SM; Columbia University Mailman School of Public Health, New York, NY, 10032, United States., Han J; Columbia University Mailman School of Public Health, New York, NY, 10032, United States., Kuriakose N; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States.; Department of Medicine, James J. Peters Bronx VA Medical Center, Bronx, NY, 10468, United States., Yamamoto NK; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States., Kugel S; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States., Jamison JK; Weill Medical College, Cornell University, New York, NY, 10065, United States., Manji GA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States., Schwartz GJ; Case Comprehensive Cancer Center, Cleveland, OH, 44106, United States., Oberstein PE; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States., Bates SE; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States.; Department of Medicine, James J. Peters Bronx VA Medical Center, Bronx, NY, 10468, United States.
Source: The oncologist [Oncologist] 2026 Mar 09; Vol. 31 (4).
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase 2 study of azacitidine plus pembrolizumab as second-line treatment in patients with locally advanced or metastatic pancreatic ductal adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Safyan+RA%22">Safyan RA</searchLink>; University of Washington School of Medicine, Seattle, WA, 98195, United States.; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States.<br /><searchLink fieldCode="AU" term="%22White+RA%22">White RA</searchLink>; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States.<br /><searchLink fieldCode="AU" term="%22Gonda+TA%22">Gonda TA</searchLink>; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States.<br /><searchLink fieldCode="AU" term="%22Lee+SM%22">Lee SM</searchLink>; Columbia University Mailman School of Public Health, New York, NY, 10032, United States.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Columbia University Mailman School of Public Health, New York, NY, 10032, United States.<br /><searchLink fieldCode="AU" term="%22Kuriakose+N%22">Kuriakose N</searchLink>; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States.; Department of Medicine, James J. Peters Bronx VA Medical Center, Bronx, NY, 10468, United States.<br /><searchLink fieldCode="AU" term="%22Yamamoto+NK%22">Yamamoto NK</searchLink>; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States.<br /><searchLink fieldCode="AU" term="%22Kugel+S%22">Kugel S</searchLink>; Fred Hutchinson Cancer Center, Seattle, WA, 98109, United States.<br /><searchLink fieldCode="AU" term="%22Jamison+JK%22">Jamison JK</searchLink>; Weill Medical College, Cornell University, New York, NY, 10065, United States.<br /><searchLink fieldCode="AU" term="%22Manji+GA%22">Manji GA</searchLink>; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States.<br /><searchLink fieldCode="AU" term="%22Schwartz+GJ%22">Schwartz GJ</searchLink>; Case Comprehensive Cancer Center, Cleveland, OH, 44106, United States.<br /><searchLink fieldCode="AU" term="%22Oberstein+PE%22">Oberstein PE</searchLink>; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, 10016, United States.<br /><searchLink fieldCode="AU" term="%22Bates+SE%22">Bates SE</searchLink>; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, United States.; Department of Medicine, James J. Peters Bronx VA Medical Center, Bronx, NY, 10468, United States.
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  Data: <searchLink fieldCode="JN" term="%229607837%22">The oncologist</searchLink> [Oncologist] 2026 Mar 09; Vol. 31 (4).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607837 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1549-490X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210837159%22">10837159 </searchLink><i>NLM ISO Abbreviation: </i>Oncologist <i>Subsets: </i>MEDLINE
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        Value: 10.1093/oncolo/oyag091
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        Text: English
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              Text: 2026 Mar 09
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