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Euglena gracilis as a high-throughput screening platform for antibacterial activity, cytotoxicity and membrane permeability in a one-step and cost-effective assay.

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Title: Euglena gracilis as a high-throughput screening platform for antibacterial activity, cytotoxicity and membrane permeability in a one-step and cost-effective assay.
Authors: Pereira L; Biocenter, University of Würzburg, Würzburg, Germany., Löffler LS; Biocenter, University of Würzburg, Würzburg, Germany., H Kirsch S; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Braunschweig, Germany., Stadler M; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Braunschweig, Germany.; Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany., Sandargo B; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Braunschweig, Germany.; Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany., Holetz F; Carlos Chagas Institute (ICC), FIOCRUZ/PR, Curitiba, Brazil., Müller R; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Braunschweig, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany., Kramer S; Biocenter, University of Würzburg, Würzburg, Germany. susanne.kramer@uni-wuerzburg.de.
Source: The Journal of antibiotics [J Antibiot (Tokyo)] 2026 Jun; Vol. 79 (6), pp. 376-385. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0151115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1469 (Electronic) Linking ISSN: 00218820 NLM ISO Abbreviation: J Antibiot (Tokyo) Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1881-1469
DOI:10.1038/s41429-026-00911-5