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Evaluation of an H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccine in lactating dairy cows.

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Title: Evaluation of an H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccine in lactating dairy cows.
Authors: Santos JJS; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Souza CK; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Zanella GC; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Goulart DB; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Arruda B; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Boggiatto P; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Palmer MV; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Snyder CA; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Kristula MA; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA., Dickens C; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA., Webb TL; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA., Atkinson RK; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dadonaite B; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA., Dwivedi G; Infection Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Alameh MG; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Bloom JD; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA., Weissman D; Infection Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Althouse GC; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA., Baker AL; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA., Hensley SE; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 04. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Evaluation of an H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccine in lactating dairy cows.
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  Data: <searchLink fieldCode="AU" term="%22Santos+JJS%22">Santos JJS</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Souza+CK%22">Souza CK</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Zanella+GC%22">Zanella GC</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Goulart+DB%22">Goulart DB</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Arruda+B%22">Arruda B</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Boggiatto+P%22">Boggiatto P</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+MV%22">Palmer MV</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Snyder+CA%22">Snyder CA</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Kristula+MA%22">Kristula MA</searchLink>; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dickens+C%22">Dickens C</searchLink>; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA.<br /><searchLink fieldCode="AU" term="%22Webb+TL%22">Webb TL</searchLink>; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA.<br /><searchLink fieldCode="AU" term="%22Atkinson+RK%22">Atkinson RK</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Dadonaite+B%22">Dadonaite B</searchLink>; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dwivedi+G%22">Dwivedi G</searchLink>; Infection Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Alameh+MG%22">Alameh MG</searchLink>; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bloom+JD%22">Bloom JD</searchLink>; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Weissman+D%22">Weissman D</searchLink>; Infection Disease Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute of RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Althouse+GC%22">Althouse GC</searchLink>; Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA.<br /><searchLink fieldCode="AU" term="%22Baker+AL%22">Baker AL</searchLink>; National Animal Disease Center - United States Department of Agriculture, Agricultural Research Service, Ames, IA, USA.<br /><searchLink fieldCode="AU" term="%22Hensley+SE%22">Hensley SE</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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