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An autoimmunity-associated allele of PTPN22 enhances innate antiviral immunity to protect against acute coronavirus infection.

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Title: An autoimmunity-associated allele of PTPN22 enhances innate antiviral immunity to protect against acute coronavirus infection.
Authors: Bevis AM; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., Rosa KJLH; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., Schwarting N; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., Cockerham TR; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., Kerr CM; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., More S; Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078., Fehr AR; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045., Orozco RC; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 24; Vol. 123 (12), pp. e2519903123. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An autoimmunity-associated allele of PTPN22 enhances innate antiviral immunity to protect against acute coronavirus infection.
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  Data: <searchLink fieldCode="AU" term="%22Bevis+AM%22">Bevis AM</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22Rosa+KJLH%22">Rosa KJLH</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22Schwarting+N%22">Schwarting N</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22Cockerham+TR%22">Cockerham TR</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22Kerr+CM%22">Kerr CM</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22More+S%22">More S</searchLink>; Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078.<br /><searchLink fieldCode="AU" term="%22Fehr+AR%22">Fehr AR</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.<br /><searchLink fieldCode="AU" term="%22Orozco+RC%22">Orozco RC</searchLink>; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Mar 24; Vol. 123 (12), pp. e2519903123. <i>Date of Electronic Publication: </i>2026 Mar 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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        Value: 10.1073/pnas.2519903123
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              Text: 2026 Mar 24
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