Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice.
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| Title: | Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice. |
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| Authors: | Bragg RM; Department of Neurology, University of Washington, Seattle, WA 98104, USA., Landles C; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Smith EJ; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Osborne GF; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Mathews EW; Department of Neurology, University of Washington, Seattle, WA 98104, USA., Cantle JP; Department of Neurology, University of Washington, Seattle, WA 98104, USA., Bates GP; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Carroll JB; Department of Neurology, University of Washington, Seattle, WA 98104, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2026 Mar 18; Vol. 18 (841), pp. eadv0702. Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41849580 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bragg+RM%22">Bragg RM</searchLink>; Department of Neurology, University of Washington, Seattle, WA 98104, USA.<br /><searchLink fieldCode="AU" term="%22Landles+C%22">Landles C</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Smith+EJ%22">Smith EJ</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Osborne+GF%22">Osborne GF</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Mathews+EW%22">Mathews EW</searchLink>; Department of Neurology, University of Washington, Seattle, WA 98104, USA.<br /><searchLink fieldCode="AU" term="%22Cantle+JP%22">Cantle JP</searchLink>; Department of Neurology, University of Washington, Seattle, WA 98104, USA.<br /><searchLink fieldCode="AU" term="%22Bates+GP%22">Bates GP</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Carroll+JB%22">Carroll JB</searchLink>; Department of Neurology, University of Washington, Seattle, WA 98104, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Mar 18; Vol. 18 (841), pp. eadv0702. <i>Date of Electronic Publication: </i>2026 Mar 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41849580 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scitranslmed.adv0702 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eadv0702 Titles: – TitleFull: Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington's disease mice. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bragg RM – PersonEntity: Name: NameFull: Landles C – PersonEntity: Name: NameFull: Smith EJ – PersonEntity: Name: NameFull: Osborne GF – PersonEntity: Name: NameFull: Mathews EW – PersonEntity: Name: NameFull: Cantle JP – PersonEntity: Name: NameFull: Bates GP – PersonEntity: Name: NameFull: Carroll JB IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 03 Text: 2026 Mar 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1946-6242 Numbering: – Type: volume Value: 18 – Type: issue Value: 841 Titles: – TitleFull: Science translational medicine Type: main |
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