Patient-derived xenograft models of primary breast cancer for preclinical evaluation of neoadjuvant therapies.
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| Title: | Patient-derived xenograft models of primary breast cancer for preclinical evaluation of neoadjuvant therapies. |
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| Authors: | Hutten SJ; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Chao X; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Badoux M; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Eijkman T; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Sheinman M; Institute of Advanced Studies, Sevastopol State University, Sevastopol, Russia., de Bruijn R; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.; Division of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands., Herencia-Ropero A; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain.; Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona, Barcelona, Spain., Llop-Guevara A; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain., Lutz C; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Wesseling J; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Division of Diagnostic Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam 1066CX, Netherlands., Serra V; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain., van Rheenen J; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands., Scheele CLGJ; Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Leuven 3000, Belgium., Jonkers J; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands. |
| Corporate Authors: | Grand Challenge PRECISION Consortium |
| Source: | Science translational medicine [Sci Transl Med] 2026 Mar 18; Vol. 18 (841), pp. eads9088. Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41849582 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Patient-derived xenograft models of primary breast cancer for preclinical evaluation of neoadjuvant therapies. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hutten+SJ%22">Hutten SJ</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Chao+X%22">Chao X</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Badoux+M%22">Badoux M</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Eijkman+T%22">Eijkman T</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sheinman+M%22">Sheinman M</searchLink>; Institute of Advanced Studies, Sevastopol State University, Sevastopol, Russia.<br /><searchLink fieldCode="AU" term="%22de+Bruijn+R%22">de Bruijn R</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.; Division of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.<br /><searchLink fieldCode="AU" term="%22Herencia-Ropero+A%22">Herencia-Ropero A</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain.; Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Llop-Guevara+A%22">Llop-Guevara A</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain.<br /><searchLink fieldCode="AU" term="%22Lutz+C%22">Lutz C</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wesseling+J%22">Wesseling J</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Division of Diagnostic Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam 1066CX, Netherlands.<br /><searchLink fieldCode="AU" term="%22Serra+V%22">Serra V</searchLink>; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain.<br /><searchLink fieldCode="AU" term="%22van+Rheenen+J%22">van Rheenen J</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Scheele+CLGJ%22">Scheele CLGJ</searchLink>; Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Leuven 3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Jonkers+J%22">Jonkers J</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam 1066CX, Netherlands.; Oncode Institute, Amsterdam, Netherlands. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Grand+Challenge+PRECISION+Consortium%22">Grand Challenge PRECISION Consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Mar 18; Vol. 18 (841), pp. eads9088. <i>Date of Electronic Publication: </i>2026 Mar 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41849582 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scitranslmed.ads9088 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eads9088 Titles: – TitleFull: Patient-derived xenograft models of primary breast cancer for preclinical evaluation of neoadjuvant therapies. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hutten SJ – PersonEntity: Name: NameFull: Chao X – PersonEntity: Name: NameFull: Badoux M – PersonEntity: Name: NameFull: Eijkman T – PersonEntity: Name: NameFull: Sheinman M – PersonEntity: Name: NameFull: de Bruijn R – PersonEntity: Name: NameFull: Herencia-Ropero A – PersonEntity: Name: NameFull: Llop-Guevara A – PersonEntity: Name: NameFull: Lutz C – PersonEntity: Name: NameFull: Wesseling J – PersonEntity: Name: NameFull: Serra V – PersonEntity: Name: NameFull: van Rheenen J – PersonEntity: Name: NameFull: Scheele CLGJ – PersonEntity: Name: NameFull: Jonkers J IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 03 Text: 2026 Mar 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1946-6242 Numbering: – Type: volume Value: 18 – Type: issue Value: 841 Titles: – TitleFull: Science translational medicine Type: main |
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