Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia.
Saved in:
| Title: | Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia. |
|---|---|
| Authors: | Le BV; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Vekariya U; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Toma MM; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Nieborowska-Skorska M; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Caron MC; CHU de Québec Research Centre (Oncology Division, Hôpital Enfant-Jesus) and Laval University Cancer Research Center, Québec City, QC G1V 4G2, Canada., Gozdecka M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Haydar Z; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Walsh M; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA; Nuclear Dynamics and Cancer Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Ghosh J; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Vaughan-Williams E; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Podszywalow-Bartnicka P; Laboratory of Cytometry, Nencki Institute of Experimental Biology Polish Academy of Sciences, 02-093 Warsaw, Poland., Kukuyan AM; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Ziolkowska S; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Atkins J; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., Hadzijusufovic E; Department for Companion Animals & Horses, Clinic for Internal Medicine and Infectious Diseases, University of Veterinary Medicine Vienna, Vienna 1210, Austria; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna 1090, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna 1990, Austria., Chandramouly G; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Nejati R; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Piwocka K; Laboratory of Cytometry, Nencki Institute of Experimental Biology Polish Academy of Sciences, 02-093 Warsaw, Poland., Pomerantz R; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Vassiliou GS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Huntly BJP; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK., Valent P; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna 1090, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna 1990, Austria., Wasik M; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA., Bellacosa A; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, USA., Masson JY; CHU de Québec Research Centre (Oncology Division, Hôpital Enfant-Jesus) and Laval University Cancer Research Center, Québec City, QC G1V 4G2, Canada., Gupta GP; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Skorski T; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA; Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Electronic address: tskorski@temple.edu. |
| Source: | Cell reports. Medicine [Cell Rep Med] 2026 Mar 17; Vol. 7 (3), pp. 102687. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
