Superior efficacy and comparable safety of calcipotriol plus betamethasone dipropionate foam vs. ointment in Chinese patients with plaque psoriasis: A randomized phase 3 trial.

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Title: Superior efficacy and comparable safety of calcipotriol plus betamethasone dipropionate foam vs. ointment in Chinese patients with plaque psoriasis: A randomized phase 3 trial.
Authors: Cai L; Department of Dermatology, Peking University People's Hospital, Beijing 100044, China., Zhang F; Dermatology Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250022, China., Zhang G; Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China., Lin B; Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China., Huang K; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China., Li Y; Department of Dermatology, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China., Wang J; Department of Dermatology, Ningbo No. 2 Hospital, Ningbo, Zhejiang 315010, China., Wan J; Department of Dermatology, Guangdong Provincial People's Hospital, Guangzhou, Guangdong 510080, China., Yin W; Department of Dermatology, The First Hospital of Jiaxing, Jiaxing, Zhejiang 314001, China., Zhang G; Department of Dermatology, Baotou Center Hospital, Baotou, Inner Mongolia 014040, China., Ding Y; Shanghai Skin Disease Hospital, Shanghai 200443, China., Meng Z; Department of Dermatology, Shiyan Renmin Hospital, Shiyan, Hubei 442000, China., Xu A; Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang 310009, China., Li L; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Zhu X; Department of Dermatology, Wuxi Second Hospital, Nanjing Medical University, Wuxi, Jiangsu 214002, China., Zhou Y; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China., Chen R; Department of Dermatology, Nanyang First People's Hospital, Nanyang, Henan 473010, China., Duan X; Department of Dermatology, Affiliated Hospital of Chengde Medical University, Chengde, Hebei 067000, China., Yu C; Department of Dermatology, Suining Central Hospital, Suining, Sichuan 629000, China., Cheng H; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, China., Wang L; Department of Dermatology, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250013, China., Yan M; Department of Dermatology, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, China., Pan W; Department of Dermatology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, China., Zhu X; Department of Dermatology, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu 225001, China., Li Z; Department of Dermatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China., Han H; Department of Dermatology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China., Zhang M; Department of Dermatology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, China., Li S; Department of Dermatology, The First Hospital of Jilin University, Changchun, Jilin 130021, China., Diao Q; Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China., Tao J; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China., Yan W; Department of Dermatology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China., Xiao R; Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China., Zhang J; Department of Dermatology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China., Yang B; Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong 510091, China., Qiao J; Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China., Man X; Department of Dermatology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China., Wang Z; Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China., Qin L; Department of Dermatology, Cangzhou People's Hospital, Cangzhou, Hebei 061000, China., Lyu X; Department of Dermatology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010050, China., Jørgensen AEM; LEO Pharma A/S, Ballerup DK-2750, Denmark., Kurvits M; LEO Pharma A/S, Ballerup DK-2750, Denmark., Andersen JS; LEO Pharma A/S, Ballerup DK-2750, Denmark., Zhang J; Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.
Source: Chinese medical journal [Chin Med J (Engl)] 2026 Mar 17. Date of Electronic Publication: 2026 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2542-5641 (Electronic) Linking ISSN: 03666999 NLM ISO Abbreviation: Chin Med J (Engl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Superior efficacy and comparable safety of calcipotriol plus betamethasone dipropionate foam vs. ointment in Chinese patients with plaque psoriasis: A randomized phase 3 trial.
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  Data: <searchLink fieldCode="AU" term="%22Cai+L%22">Cai L</searchLink>; Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Dermatology Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250022, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China.<br /><searchLink fieldCode="AU" term="%22Huang+K%22">Huang K</searchLink>; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Dermatology, The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Dermatology, Ningbo No. 2 Hospital, Ningbo, Zhejiang 315010, China.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; Department of Dermatology, Guangdong Provincial People's Hospital, Guangzhou, Guangdong 510080, China.<br /><searchLink fieldCode="AU" term="%22Yin+W%22">Yin W</searchLink>; Department of Dermatology, The First Hospital of Jiaxing, Jiaxing, Zhejiang 314001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Department of Dermatology, Baotou Center Hospital, Baotou, Inner Mongolia 014040, China.<br /><searchLink fieldCode="AU" term="%22Ding+Y%22">Ding Y</searchLink>; Shanghai Skin Disease Hospital, Shanghai 200443, China.<br /><searchLink fieldCode="AU" term="%22Meng+Z%22">Meng Z</searchLink>; Department of Dermatology, Shiyan Renmin Hospital, Shiyan, Hubei 442000, China.<br /><searchLink fieldCode="AU" term="%22Xu+A%22">Xu A</searchLink>; Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang 310009, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Dermatology, Wuxi Second Hospital, Nanjing Medical University, Wuxi, Jiangsu 214002, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Dermatology, Nanyang First People's Hospital, Nanyang, Henan 473010, China.<br /><searchLink fieldCode="AU" term="%22Duan+X%22">Duan X</searchLink>; Department of Dermatology, Affiliated Hospital of Chengde Medical University, Chengde, Hebei 067000, China.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Department of Dermatology, Suining Central Hospital, Suining, Sichuan 629000, China.<br /><searchLink fieldCode="AU" term="%22Cheng+H%22">Cheng H</searchLink>; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Dermatology, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250013, China.<br /><searchLink fieldCode="AU" term="%22Yan+M%22">Yan M</searchLink>; Department of Dermatology, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, China.<br /><searchLink fieldCode="AU" term="%22Pan+W%22">Pan W</searchLink>; Department of Dermatology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, China.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Dermatology, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu 225001, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Dermatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.<br /><searchLink fieldCode="AU" term="%22Han+H%22">Han H</searchLink>; Department of Dermatology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Department of Dermatology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Dermatology, The First Hospital of Jilin University, Changchun, Jilin 130021, China.<br /><searchLink fieldCode="AU" term="%22Diao+Q%22">Diao Q</searchLink>; Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.<br /><searchLink fieldCode="AU" term="%22Tao+J%22">Tao J</searchLink>; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.<br /><searchLink fieldCode="AU" term="%22Yan+W%22">Yan W</searchLink>; Department of Dermatology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.<br /><searchLink fieldCode="AU" term="%22Xiao+R%22">Xiao R</searchLink>; Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Dermatology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China.<br /><searchLink fieldCode="AU" term="%22Yang+B%22">Yang B</searchLink>; Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong 510091, China.<br /><searchLink fieldCode="AU" term="%22Qiao+J%22">Qiao J</searchLink>; Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.<br /><searchLink fieldCode="AU" term="%22Man+X%22">Man X</searchLink>; Department of Dermatology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.<br /><searchLink fieldCode="AU" term="%22Qin+L%22">Qin L</searchLink>; 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