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Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection.

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Title: Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection.
Authors: Hodgson RE; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Huang WP; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Lang R; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Kumar V; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., An H; Cardiff University, Cardiff, UK., Stender EGP; Fida Biosystems ApS, Søborg, Denmark., Chalakova ZP; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK.; The Francis Crick Institute, London, UK., Driver MD; Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands.; Big Chemistry Foundation, Nijmegen, the Netherlands., Sanchez Avila A; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Ellis BCS; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Day E; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Rayment JA; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Baeg K; Molecular Systems Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Strange A; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Moll T; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Wright GSA; School of Life Sciences, University of Essex, Essex, UK., van Vugt JJFA; University Medical Center Utrecht, Utrecht, the Netherlands., Allen SP; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Locker N; The Pirbright Institute, Pirbright, Surrey, UK., Pitout I; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, Western Australia, Australia., Fletcher S; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, Western Australia, Australia., Onck PR; Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands., Duss O; Molecular Systems Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Cooper-Knock J; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK., Shelkovnikova TA; Sheffield Institute for Translational Neuroscience and Neuroscience Institute, University of Sheffield, Sheffield, UK. t.shelkovnikova@sheffield.ac.uk.
Corporate Authors: Project MinE ALS Sequencing Consortium
Source: Nature cell biology [Nat Cell Biol] 2026 Apr; Vol. 28 (4), pp. 754-770. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2026 Apr; Vol. 28 (4), pp. 754-770. <i>Date of Electronic Publication: </i>2026 Mar 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Macmillan+Magazines+Ltd%22">Macmillan Magazines Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100890575 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4679 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214657392%22">14657392 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cell Biol <i>Subsets: </i>MEDLINE
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