TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): study protocol for a stepped-wedge, cluster-randomized clinical trial.
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| Title: | TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): study protocol for a stepped-wedge, cluster-randomized clinical trial. |
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| Authors: | De Zoysa PDWD; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Weerasinghe SA; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Gamage J; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Iglesias-Ussel MD; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Olague S; Duke Clinical Research Institute, Duke University, Durham, NC, USA., Obale A; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA., Gallis JA; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Palangasinghe D; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Senadheera B; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Vasana S; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Nix C; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Bodinayake CK; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA., Nagahawatte ADS; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Wijayaratne WMDGB; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Department of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Kurukulasooriya MRP; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Premamali M; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Dilshan UHBY; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka., Ngocho J; Kilimanjaro Christian Medical Centre, Moshi, Tanzania., Østbye T; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Family Medicine and Community Health, Duke University, Durham, NC, USA., Laber EB; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Watt MH; Department of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, USA., Myers E; Duke Clinical Research Institute, Duke University, Durham, NC, USA.; Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC, USA., Woods CW; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Global Health Institute, Duke University, Durham, NC, USA., Naggie S; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Duke University, Durham, NC, USA., Kenny A; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Chakraborty H; Duke Clinical Research Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Tillekeratne LG; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. gayani.tillekeratne@duke.edu.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. gayani.tillekeratne@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA. gayani.tillekeratne@duke.edu.; Duke Global Health Institute, Duke University, Durham, NC, USA. gayani.tillekeratne@duke.edu. |
| Source: | Trials [Trials] 2026 Mar 18; Vol. 27 (1). Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41851897 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): study protocol for a stepped-wedge, cluster-randomized clinical trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22De+Zoysa+PDWD%22">De Zoysa PDWD</searchLink>; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Weerasinghe+SA%22">Weerasinghe SA</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Gamage+J%22">Gamage J</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Iglesias-Ussel+MD%22">Iglesias-Ussel MD</searchLink>; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Olague+S%22">Olague S</searchLink>; Duke Clinical Research Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Obale+A%22">Obale A</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gallis+JA%22">Gallis JA</searchLink>; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Palangasinghe+D%22">Palangasinghe D</searchLink>; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Senadheera+B%22">Senadheera B</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Vasana+S%22">Vasana S</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Nix+C%22">Nix C</searchLink>; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Bodinayake+CK%22">Bodinayake CK</searchLink>; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Nagahawatte+ADS%22">Nagahawatte ADS</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Wijayaratne+WMDGB%22">Wijayaratne WMDGB</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Department of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Kurukulasooriya+MRP%22">Kurukulasooriya MRP</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Premamali+M%22">Premamali M</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Dilshan+UHBY%22">Dilshan UHBY</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Ngocho+J%22">Ngocho J</searchLink>; Kilimanjaro Christian Medical Centre, Moshi, Tanzania.<br /><searchLink fieldCode="AU" term="%22Østbye+T%22">Østbye T</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Family Medicine and Community Health, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Laber+EB%22">Laber EB</searchLink>; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Watt+MH%22">Watt MH</searchLink>; Department of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Myers+E%22">Myers E</searchLink>; Duke Clinical Research Institute, Duke University, Durham, NC, USA.; Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Woods+CW%22">Woods CW</searchLink>; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Global Health Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Naggie+S%22">Naggie S</searchLink>; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kenny+A%22">Kenny A</searchLink>; Duke Global Health Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Chakraborty+H%22">Chakraborty H</searchLink>; Duke Clinical Research Institute, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Tillekeratne+LG%22">Tillekeratne LG</searchLink>; Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. gayani.tillekeratne@duke.edu.; Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. gayani.tillekeratne@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA. gayani.tillekeratne@duke.edu.; Duke Global Health Institute, Duke University, Durham, NC, USA. gayani.tillekeratne@duke.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2026 Mar 18; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Mar 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial Protocol – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41851897 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13063-026-09628-0 Languages: – Code: eng Text: English Titles: – TitleFull: TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): study protocol for a stepped-wedge, cluster-randomized clinical trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: De Zoysa PDWD – PersonEntity: Name: NameFull: Weerasinghe SA – PersonEntity: Name: NameFull: Gamage J – PersonEntity: Name: NameFull: Iglesias-Ussel MD – PersonEntity: Name: NameFull: Olague S – PersonEntity: Name: NameFull: Obale A – PersonEntity: Name: NameFull: Gallis JA – PersonEntity: Name: NameFull: Palangasinghe D – PersonEntity: Name: NameFull: Senadheera B – PersonEntity: Name: NameFull: Vasana S – PersonEntity: Name: NameFull: Nix C – PersonEntity: Name: NameFull: Bodinayake CK – PersonEntity: Name: NameFull: Nagahawatte ADS – PersonEntity: Name: NameFull: Wijayaratne WMDGB – PersonEntity: Name: NameFull: Kurukulasooriya MRP – PersonEntity: Name: NameFull: Premamali M – PersonEntity: Name: NameFull: Dilshan UHBY – PersonEntity: Name: NameFull: Ngocho J – PersonEntity: Name: NameFull: Østbye T – PersonEntity: Name: NameFull: Laber EB – PersonEntity: Name: NameFull: Watt MH – PersonEntity: Name: NameFull: Myers E – PersonEntity: Name: NameFull: Woods CW – PersonEntity: Name: NameFull: Naggie S – PersonEntity: Name: NameFull: Kenny A – PersonEntity: Name: NameFull: Chakraborty H – PersonEntity: Name: NameFull: Tillekeratne LG IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 03 Text: 2026 Mar 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1745-6215 Numbering: – Type: volume Value: 27 – Type: issue Value: 1 Titles: – TitleFull: Trials Type: main |
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