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Tau-PET imaging and blood biomarkers reveal early tauopathy in special operations forces exposed to repetitive blast.

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Title: Tau-PET imaging and blood biomarkers reveal early tauopathy in special operations forces exposed to repetitive blast.
Authors: Lora SJ; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada., Rhind SG; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.; Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON M5S 2W6, Canada., Watling SE; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada., Narciso L; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada., Warsh J; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada., Vartanian O; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.; Department of Psychology, University of Toronto, Toronto, ON M5S 2E5, Canada., McCluskey T; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada., Tyndale RF; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada., Tartaglia MC; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON M5S 1A8, Canada., Shiu MY; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada., Vallée I; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada., Crouzat M; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada., Vergie I; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada., Vasdev N; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Azrieli Centre for Neuro-Radiochemistry, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada., Boileau I; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada.
Source: Brain communications [Brain Commun] 2026 Mar 13; Vol. 8 (2), pp. fcag070. Date of Electronic Publication: 2026 Mar 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Tau-PET imaging and blood biomarkers reveal early tauopathy in special operations forces exposed to repetitive blast.
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  Data: <searchLink fieldCode="AU" term="%22Lora+SJ%22">Lora SJ</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.<br /><searchLink fieldCode="AU" term="%22Rhind+SG%22">Rhind SG</searchLink>; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.; Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON M5S 2W6, Canada.<br /><searchLink fieldCode="AU" term="%22Watling+SE%22">Watling SE</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.<br /><searchLink fieldCode="AU" term="%22Narciso+L%22">Narciso L</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Warsh+J%22">Warsh J</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada.<br /><searchLink fieldCode="AU" term="%22Vartanian+O%22">Vartanian O</searchLink>; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.; Department of Psychology, University of Toronto, Toronto, ON M5S 2E5, Canada.<br /><searchLink fieldCode="AU" term="%22McCluskey+T%22">McCluskey T</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Tyndale+RF%22">Tyndale RF</searchLink>; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada.<br /><searchLink fieldCode="AU" term="%22Tartaglia+MC%22">Tartaglia MC</searchLink>; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Shiu+MY%22">Shiu MY</searchLink>; Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.<br /><searchLink fieldCode="AU" term="%22Vallée+I%22">Vallée I</searchLink>; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada.<br /><searchLink fieldCode="AU" term="%22Crouzat+M%22">Crouzat M</searchLink>; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada.<br /><searchLink fieldCode="AU" term="%22Vergie+I%22">Vergie I</searchLink>; National Defence and the Canadian Armed Forces, Canadian Special Operations Forces Command, Ottawa, ON K1N 8T7, Canada.<br /><searchLink fieldCode="AU" term="%22Vasdev+N%22">Vasdev N</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Azrieli Centre for Neuro-Radiochemistry, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.<br /><searchLink fieldCode="AU" term="%22Boileau+I%22">Boileau I</searchLink>; Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 3H2, Canada.; Campbell Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada.; Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 3K3, Canada.
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        Value: 10.1093/braincomms/fcag070
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