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A Method to Enrich Functional Human Paneth Cells in Induced Pluripotent Stem Cell-Derived Intestinal Organoids.

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Title: A Method to Enrich Functional Human Paneth Cells in Induced Pluripotent Stem Cell-Derived Intestinal Organoids.
Authors: Patel S; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California., Wagner MS; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California., Bay O; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California., Wong Valencia CE; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California., Zgarbova E; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California., Rodriguez CI; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California., Leal DN; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Yamashita M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Devkota S; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine, Cedars-Sinai Medical Center, Human Microbiome Research Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Michelsen KS; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Targan SR; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Barrett RJ; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address: Robert.Barrett@csmc.edu.
Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (7), pp. 101769. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE; In Process
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  Data: A Method to Enrich Functional Human Paneth Cells in Induced Pluripotent Stem Cell-Derived Intestinal Organoids.
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  Data: <searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Wagner+MS%22">Wagner MS</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Bay+O%22">Bay O</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Wong+Valencia+CE%22">Wong Valencia CE</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Zgarbova+E%22">Zgarbova E</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Rodriguez+CI%22">Rodriguez CI</searchLink>; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Leal+DN%22">Leal DN</searchLink>; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Yamashita+M%22">Yamashita M</searchLink>; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Devkota+S%22">Devkota S</searchLink>; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine, Cedars-Sinai Medical Center, Human Microbiome Research Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Michelsen+KS%22">Michelsen KS</searchLink>; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Targan+SR%22">Targan SR</searchLink>; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Barrett+RJ%22">Barrett RJ</searchLink>; Cedars-Sinai Medical Center, Board of Governors Regenerative Medicine Institute, Los Angeles, California; Cedars-Sinai Medical Center, F. Widjaja Inflammatory Bowel Disease Institute, Los Angeles, California; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address: Robert.Barrett@csmc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101648302%22">Cellular and molecular gastroenterology and hepatology</searchLink> [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (7), pp. 101769. <i>Date of Electronic Publication: </i>2026 Mar 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Gastroenterological+Association%22">American Gastroenterological Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101648302 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-345X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222352345X%22">2352345X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Gastroenterol Hepatol <i>Subsets: </i>MEDLINE; In Process
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