Cost-effectiveness of proactive therapeutic drug monitoring of maintenance infliximab treatment in patients with immune-mediated inflammatory diseases: results from a randomised controlled trial.

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Title: Cost-effectiveness of proactive therapeutic drug monitoring of maintenance infliximab treatment in patients with immune-mediated inflammatory diseases: results from a randomised controlled trial.
Authors: Holly T; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway., Kirkesaether Brun M; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Jørgensen KK; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway., Goll GL; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Sexton J; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Gehin JE; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Kvien TK; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Jahnsen J; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway., Provan SA; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Department of Public Health and Sport Sciences, Faculty of Social and Health Sciences, University of Inland Norway, Elverum, Norway., Bolstad N; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Aas E; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Health Services Research, Norwegian Institute of Public Health, Oslo, Norway., Haavardsholm EA; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Kristiansen IS; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Unit of General Practice, University of Southern Denmark, Odense, Denmark., Syversen SW; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway., Hagen G; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway gunhild.hagen@diakonsyk.no.; Department of Health Services Research, Norwegian Institute of Public Health, Oslo, Norway.
Source: RMD open [RMD Open] 2026 Mar 19; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101662038 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-5933 (Electronic) Linking ISSN: 20565933 NLM ISO Abbreviation: RMD Open Subsets: MEDLINE
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  Data: Cost-effectiveness of proactive therapeutic drug monitoring of maintenance infliximab treatment in patients with immune-mediated inflammatory diseases: results from a randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Holly+T%22">Holly T</searchLink>; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kirkesaether+Brun+M%22">Kirkesaether Brun M</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Jørgensen+KK%22">Jørgensen KK</searchLink>; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway.<br /><searchLink fieldCode="AU" term="%22Goll+GL%22">Goll GL</searchLink>; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Sexton+J%22">Sexton J</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Gehin+JE%22">Gehin JE</searchLink>; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kvien+TK%22">Kvien TK</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Jahnsen+J%22">Jahnsen J</searchLink>; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway.<br /><searchLink fieldCode="AU" term="%22Provan+SA%22">Provan SA</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Department of Public Health and Sport Sciences, Faculty of Social and Health Sciences, University of Inland Norway, Elverum, Norway.<br /><searchLink fieldCode="AU" term="%22Bolstad+N%22">Bolstad N</searchLink>; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Aas+E%22">Aas E</searchLink>; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Health Services Research, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Haavardsholm+EA%22">Haavardsholm EA</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kristiansen+IS%22">Kristiansen IS</searchLink>; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research Unit of General Practice, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Syversen+SW%22">Syversen SW</searchLink>; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hagen+G%22">Hagen G</searchLink>; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway gunhild.hagen@diakonsyk.no.; Department of Health Services Research, Norwegian Institute of Public Health, Oslo, Norway.
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        Text: English
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