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International testing and refinement of AI algorithms predicting acute leukemia subtypes from routine laboratory data.

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Title: International testing and refinement of AI algorithms predicting acute leukemia subtypes from routine laboratory data.
Authors: Turki AT; Computational Hematology Lab, Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany. amin.turki@uk-essen.de.; Department of Hematology and Oncology, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany. amin.turki@uk-essen.de.; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany. amin.turki@uk-essen.de., Fan Y; The First Affiliated Hospital of Soochow University, Suzhou, China., Hernández-Sánchez A; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Silva W; Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil., Fleming S; The Alfred Hospital, Melbourne, Australia., Yalcin K; Bahcesehir University Medicalpark Goztepe Hospital, Department of Pediatric Hematology/Oncology, Istanbul, Turkey., Van Elssen CHMJ; Maastricht University Medical Center, Department of Internal Medicine, Division of Hematology & GROW research, Institute of Oncology and Reproduction, Maastricht, The Netherlands., Madanat Y; University of Texas Southwestern, Dallas, USA., Karasek M; Department of Hematology, Cell Therapies and Internal Medicine, Wroclaw Medical University, Wrocław, Poland.; Department of Hematology, University Hospital N° 2 in Bydgoszcz, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland., Aljurf M; King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia., Della Porta MG; IRCCS Humanitas Research Hospital & Humanitas University Milan, Milan, Italy., Martinez-Roca A; Department of Hematology, Hospital Clínic Barcelona, Barcelona, Spain., Guarnera L; Tor Vergata University Roma, Rome, Italy., Steffen K; Central Laboratory Division, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany., Antoniou E; Department of Pediatrics III, University Hospital Essen, Essen, Germany., Rivas MM; Hospital Universitario Austral, Buenos-Aires, Argentina., Mishra DK; Tata Medical Center, Kolkata, India., Blum AT; Department of Hematology and Oncology, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany., Manantsoa SN; Hematology Department, University Hospital Joseph Ravoahangy Andrianavalona of Antananarivo, Antananarivo, Madagascar., Adiat A; Lagos University, Lagos, Nigeria., Enshaei A; Leukaemia Research Cytogenomics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Thol F; Department of Hematology, Hannover Medical School, Hannover, Germany., Voso MT; Tor Vergata University Roma, Rome, Italy., Chen J; The First Affiliated Hospital of Soochow University, Suzhou, China., Elhassan TA; King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.; Alfaisal University, Riyadh, Saudi Arabia., Moorman AV; Leukaemia Research Cytogenomics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Vidriales MB; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Neuendorff NR; Department of Hematology and Oncology, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany., Koc A; Marmara University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Istanbul, Turkey., Mishra P; Tata Medical Center, Kolkata, India., Strumberg D; Department of Hematology and Oncology, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany., Fourmanov RS; Maastricht University Medical Center, Department of Internal Medicine, Division of Hematology & GROW research, Institute of Oncology and Reproduction, Maastricht, The Netherlands., Heine L; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany., Kleesiek J; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany., Munárriz D; Department of Hematology, Hospital Clínic Barcelona, Barcelona, Spain., Asti G; IRCCS Humanitas Research Hospital & Humanitas University Milan, Milan, Italy., Mokoonlall M; The Alfred Hospital, Melbourne, Australia., Kometas M; University of Texas Southwestern, Dallas, USA., Rego E; Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil., Mecklenbrauck R; Department of Hematology, Hannover Medical School, Hannover, Germany., Sobas M; Department of Hematology, Cell Therapies and Internal Medicine, Wroclaw Medical University, Wrocław, Poland.; Department of Hematology, University Hospital N° 2 in Bydgoszcz, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland., Wu D; The First Affiliated Hospital of Soochow University, Suzhou, China., Nensa F; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany., Engelke M; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany.
Source: Nature communications [Nat Commun] 2026 Mar 20; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Turki+AT%22">Turki AT</searchLink>; Computational Hematology Lab, Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany. amin.turki@uk-essen.de.; Department of Hematology and Oncology, University Hospital Marienhospital, Ruhr-University Bochum, Bochum, Germany. amin.turki@uk-essen.de.; Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany. amin.turki@uk-essen.de.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; The First Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Hernández-Sánchez+A%22">Hernández-Sánchez A</searchLink>; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Silva+W%22">Silva W</searchLink>; Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Fleming+S%22">Fleming S</searchLink>; 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