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Increased VH4+JH6+ antibody heavy chain use in plasmablasts from asymptomatic multiple sclerosis patients.

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Title: Increased VH4+JH6+ antibody heavy chain use in plasmablasts from asymptomatic multiple sclerosis patients.
Authors: Benavides S; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Christley S; School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA., Telesford KM; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Smith C; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Sheffer K; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Wu Y; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Tse KM; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Greenberg HJ; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Jackson M; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Chapman C; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Dinov D; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Hardeman P; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Siva A; Department of Neurology, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey., Pelletier D; NeuroRX Research, Montreal, QC, Canada., Kantarci O; Neurology, Mayo Clinic, Rochester, MN, USA., Lebrun-Frénay C; Neurology MS Clinic Nice, Pasteur 2 University Hospital; UR2CA-URRIS, Côte d'Azur University, Nice, France., Cowell LG; School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA., Okuda DT; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Monson NL; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA. nancy.monson@utsouthwestern.edu.; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, USA. nancy.monson@utsouthwestern.edu.
Source: Genes and immunity [Genes Immun] 2026 Jun; Vol. 27 (3), pp. 341-350. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased VH4+JH6+ antibody heavy chain use in plasmablasts from asymptomatic multiple sclerosis patients.
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  Data: <searchLink fieldCode="AU" term="%22Benavides+S%22">Benavides S</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Christley+S%22">Christley S</searchLink>; School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Telesford+KM%22">Telesford KM</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sheffer+K%22">Sheffer K</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tse+KM%22">Tse KM</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+HJ%22">Greenberg HJ</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+M%22">Jackson M</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+C%22">Chapman C</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dinov+D%22">Dinov D</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hardeman+P%22">Hardeman P</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Siva+A%22">Siva A</searchLink>; Department of Neurology, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Pelletier+D%22">Pelletier D</searchLink>; NeuroRX Research, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Kantarci+O%22">Kantarci O</searchLink>; Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lebrun-Frénay+C%22">Lebrun-Frénay C</searchLink>; Neurology MS Clinic Nice, Pasteur 2 University Hospital; UR2CA-URRIS, Côte d'Azur University, Nice, France.<br /><searchLink fieldCode="AU" term="%22Cowell+LG%22">Cowell LG</searchLink>; School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Okuda+DT%22">Okuda DT</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Monson+NL%22">Monson NL</searchLink>; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA. nancy.monson@utsouthwestern.edu.; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, USA. nancy.monson@utsouthwestern.edu.
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  Data: <searchLink fieldCode="JN" term="%22100953417%22">Genes and immunity</searchLink> [Genes Immun] 2026 Jun; Vol. 27 (3), pp. 341-350. <i>Date of Electronic Publication: </i>2026 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100953417 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5470 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214664879%22">14664879 </searchLink><i>NLM ISO Abbreviation: </i>Genes Immun <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41435-026-00389-z
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      – TitleFull: Increased VH4+JH6+ antibody heavy chain use in plasmablasts from asymptomatic multiple sclerosis patients.
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              Text: 2026 Jun
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