Population pharmacokinetics of fosmidomycin and clindamycin in combination with artesunate for uncomplicated Plasmodium falciparum malaria in Gabonese children and adults.

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Title: Population pharmacokinetics of fosmidomycin and clindamycin in combination with artesunate for uncomplicated Plasmodium falciparum malaria in Gabonese children and adults.
Authors: Pfaffendorf C; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Bundesstrasse 45, 20146, Hamburg, Germany., Dejon-Agobé JC; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institut für Tropenmedizin, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany., Edoa JR; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Maïga-Ascofaré O; Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.; Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany., Ahenkan E; Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.; Department of Pharmacology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Adegnika AA; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institut für Tropenmedizin, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany., Ramharter M; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I., Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon., Wicha SG; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Bundesstrasse 45, 20146, Hamburg, Germany. sebastian.wicha@uni-hamburg.de., Mischlinger J; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I., Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Source: Malaria journal [Malar J] 2026 Mar 19; Vol. 25 (1). Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Population pharmacokinetics of fosmidomycin and clindamycin in combination with artesunate for uncomplicated Plasmodium falciparum malaria in Gabonese children and adults.
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  Data: <searchLink fieldCode="AU" term="%22Pfaffendorf+C%22">Pfaffendorf C</searchLink>; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Bundesstrasse 45, 20146, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dejon-Agobé+JC%22">Dejon-Agobé JC</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institut für Tropenmedizin, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Edoa+JR%22">Edoa JR</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Maïga-Ascofaré+O%22">Maïga-Ascofaré O</searchLink>; Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.; Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ahenkan+E%22">Ahenkan E</searchLink>; Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.; Department of Pharmacology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.<br /><searchLink fieldCode="AU" term="%22Adegnika+AA%22">Adegnika AA</searchLink>; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.; Institut für Tropenmedizin, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ramharter+M%22">Ramharter M</searchLink>; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I., Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.<br /><searchLink fieldCode="AU" term="%22Wicha+SG%22">Wicha SG</searchLink>; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Bundesstrasse 45, 20146, Hamburg, Germany. sebastian.wicha@uni-hamburg.de.<br /><searchLink fieldCode="AU" term="%22Mischlinger+J%22">Mischlinger J</searchLink>; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I., Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
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  Data: <searchLink fieldCode="JN" term="%22101139802%22">Malaria journal</searchLink> [Malar J] 2026 Mar 19; Vol. 25 (1). <i>Date of Electronic Publication: </i>2026 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101139802 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1475-2875 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214752875%22">14752875 </searchLink><i>NLM ISO Abbreviation: </i>Malar J <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar 19
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