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Recombinant vs Standard Influenza Vaccine in Adults With Severe Obesity: A Randomized Clinical Trial.

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Title: Recombinant vs Standard Influenza Vaccine in Adults With Severe Obesity: A Randomized Clinical Trial.
Authors: Loubet P; Virulence Bactérienne et Infections Chroniques, INSERM U1047, Univ Montpellier Department of Infectious and Tropical Disease, CHU Nîmes, Nîmes, France.; Inserm, F-CRIN, I-Reivac network, Paris, France., Czernichow S; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France., Giboin C; AP-HP, Hôpital Pitié-Salpêtrière, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Sultan A; Université de Montpellier, Service de Nutrition-Diabète, CHU de Montpellier, Montpellier, France., Guimard T; Médecine Post-Urgences et Infectiologie, Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France., Disse E; Centre Spécialisé de l'Obésité des HCL, Service d'Endocrinologie-Diabète-Nutrition, Hôpital Lyon Sud, Hospices Civils de Lyon, Lyon, France. Univ Lyon, CarMen Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1; FORCE Network, French Obesity Research Centre of Excellence/F-CRIN INSERM network., Tavolacci MP; Inserm, F-CRIN, I-Reivac network, Paris, France.; Univ Rouen Normandie, UMR1073 ADEN, CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France., Ben Ghezala I; Inserm, F-CRIN, I-Reivac network, Paris, France.; Centre d'Investigation Clinique INSERM 1432., Ledoux S; Université Paris Cité, Centre spécialisé de l'obésité, Assistance Publique Hôpitaux de Paris, Hôpital Louis Mourier, Colombes, France., Janssen C; Inserm, F-CRIN, I-Reivac network, Paris, France.; Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Annecy Genevois, Annecy, France., Mosbah H; Service d'Endocrinologie, Diabétologie, Nutrition, CHU Poitiers, INSERM, Centre d'Investigation Clinique CIC1402, Poitiers, 86021, France., Lefebvre M; Inserm, F-CRIN, I-Reivac network, Paris, France.; Service des Maladies Infectieuses et Tropicales, CHU de Nantes, Nantes, France., De Luca A; Service de Nutrition, CHU de Tours, Tours, France., Nguyen LBL; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France., Taillard V; Service d'Endocrinologie, CHU de Nîmes, Nîmes, France., Couster J; Centre spécialisé de l'obésité, CH de Boulogne-sur-mer, Boulogne-sur-mer, France., Duale C; Inserm, F-CRIN, I-Reivac network, Paris, France.; INSERM CIC 1405, University Hospital Clermont-Ferrand, Clermont-Ferrand, France., Carette C; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France., Rives-Lange C; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France., Zemouri S; AP-HP, Hôpital Pitié-Salpêtrière, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Desaint C; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France., Tubach F; Sorbonne Université, INSERM, Institut Pierre-Louis d'Épidémiologie et de Santé Publique, Équipe PEPITES, AP-HP, Hôpital Pitié-Salpêtrière, Département de Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Launay O; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Mar 19. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Recombinant vs Standard Influenza Vaccine in Adults With Severe Obesity: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Loubet+P%22">Loubet P</searchLink>; Virulence Bactérienne et Infections Chroniques, INSERM U1047, Univ Montpellier Department of Infectious and Tropical Disease, CHU Nîmes, Nîmes, France.; Inserm, F-CRIN, I-Reivac network, Paris, France.<br /><searchLink fieldCode="AU" term="%22Czernichow+S%22">Czernichow S</searchLink>; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Giboin+C%22">Giboin C</searchLink>; AP-HP, Hôpital Pitié-Salpêtrière, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Sultan+A%22">Sultan A</searchLink>; Université de Montpellier, Service de Nutrition-Diabète, CHU de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Guimard+T%22">Guimard T</searchLink>; Médecine Post-Urgences et Infectiologie, Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France.<br /><searchLink fieldCode="AU" term="%22Disse+E%22">Disse E</searchLink>; Centre Spécialisé de l'Obésité des HCL, Service d'Endocrinologie-Diabète-Nutrition, Hôpital Lyon Sud, Hospices Civils de Lyon, Lyon, France. Univ Lyon, CarMen Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1; FORCE Network, French Obesity Research Centre of Excellence/F-CRIN INSERM network.<br /><searchLink fieldCode="AU" term="%22Tavolacci+MP%22">Tavolacci MP</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Univ Rouen Normandie, UMR1073 ADEN, CHU Rouen, CIC-CRB 1404, F-76000 Rouen, France.<br /><searchLink fieldCode="AU" term="%22Ben+Ghezala+I%22">Ben Ghezala I</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Centre d'Investigation Clinique INSERM 1432.<br /><searchLink fieldCode="AU" term="%22Ledoux+S%22">Ledoux S</searchLink>; Université Paris Cité, Centre spécialisé de l'obésité, Assistance Publique Hôpitaux de Paris, Hôpital Louis Mourier, Colombes, France.<br /><searchLink fieldCode="AU" term="%22Janssen+C%22">Janssen C</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Annecy Genevois, Annecy, France.<br /><searchLink fieldCode="AU" term="%22Mosbah+H%22">Mosbah H</searchLink>; Service d'Endocrinologie, Diabétologie, Nutrition, CHU Poitiers, INSERM, Centre d'Investigation Clinique CIC1402, Poitiers, 86021, France.<br /><searchLink fieldCode="AU" term="%22Lefebvre+M%22">Lefebvre M</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Service des Maladies Infectieuses et Tropicales, CHU de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22De+Luca+A%22">De Luca A</searchLink>; Service de Nutrition, CHU de Tours, Tours, France.<br /><searchLink fieldCode="AU" term="%22Nguyen+LBL%22">Nguyen LBL</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France.<br /><searchLink fieldCode="AU" term="%22Taillard+V%22">Taillard V</searchLink>; Service d'Endocrinologie, CHU de Nîmes, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Couster+J%22">Couster J</searchLink>; Centre spécialisé de l'obésité, CH de Boulogne-sur-mer, Boulogne-sur-mer, France.<br /><searchLink fieldCode="AU" term="%22Duale+C%22">Duale C</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; INSERM CIC 1405, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Carette+C%22">Carette C</searchLink>; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rives-Lange+C%22">Rives-Lange C</searchLink>; Université Paris-Cité, Service de Nutrition, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zemouri+S%22">Zemouri S</searchLink>; AP-HP, Hôpital Pitié-Salpêtrière, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Desaint+C%22">Desaint C</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tubach+F%22">Tubach F</searchLink>; Sorbonne Université, INSERM, Institut Pierre-Louis d'Épidémiologie et de Santé Publique, Équipe PEPITES, AP-HP, Hôpital Pitié-Salpêtrière, Département de Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Launay+O%22">Launay O</searchLink>; Inserm, F-CRIN, I-Reivac network, Paris, France.; Université Paris Cité; Inserm, CIC 1417 ; AP-HP, Hôpital Cochin, CIC Cochin Pasteur, Paris, France.
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