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PD-1 blockade does not enhance alloimmunization after allogeneic dendritic cell vaccination in cancer patients.

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Title: PD-1 blockade does not enhance alloimmunization after allogeneic dendritic cell vaccination in cancer patients.
Authors: Planel S; R&D Department, PDC*line Pharma France, Grenoble, France., Vayssière G; R&D Department, PDC*line Pharma France, Grenoble, France., Maggipinto G; G.M. Consultant Company, Liège, Belgium., Leplus E; R&D Department, PDC*line Pharma France, Grenoble, France., Laulagnier K; R&D Department, PDC*line Pharma France, Grenoble, France., Renard F; R&D and Clinical Departments, PDC*line Pharma Belgique, Liège, Belgium., Myster F; R&D and Clinical Departments, PDC*line Pharma Belgique, Liège, Belgium., Gerard M; Human Leukocyte Antigen (HLA) Laboratory, Etablissement Français du Sang (EFS) Rhone-Alpes Auvergne, Grenoble, France., Demedts I; Pulmonary Diseases, AZ Delta Campus Rumbeke, Roeselare, Belgium., Cuppens K; Pulmonology and Thoracic Oncology Department, Jessa Hospital, Hasselt, Belgium., Pons-Tostivint E; Medical Oncology Department, Nantes University Hospital, Nantes, France., Wauters E; Respiratory Oncology Unit (Pulmonology), University Hospitals Leuven, Leuven, Belgium., Borm FJ; Department of Pulmonology, Leiden University Medical Center, Leiden, Netherlands., Sibille A; Department of Pulmonology, Centre Hospitalier Universitaire de Liège, Liège, Belgium., Colinet B; Pneumology Department, Grand Hôpital de Charleroi, Site Notre Dame, Charleroi, Belgium., Pérol M; Medical Oncology Department, Centre Léon Bérard, Lyon, France., Theelen WSME; Thoracic Oncology Department, Netherlands Cancer Institute, Amsterdam, Netherlands., Biesma B; Pulmonology, Jeroen Bosch Hospital, 's-Hertogenbosch, Netherlands., Van De Kerkhove C; Clinical Study Centre, Vitaz campus Sint-Niklaas Moerland, Sint-Niklaas, Belgium., Buchmeier E; Hematology and Oncology Department, Kliniken der Stadt Koln gGmbH, Köln, Germany., Althoff FC; Hemato-Oncology Department, Universitätsklinikum Frankfurt (Johannes-Wolfgang Goethe-Universität), Frankfurt Am Main, Germany., Derijcke S; Pulmonology: Thoracic Oncology, AZ Groeninge, Campus Kennedylaan, Kortrijk, Belgium., Moro-Sibilot D; Thoracic Oncology, Service d'Hospitalo-Universitaire de Pneumologie et Pneumo-Oncologie (SHUPP), Centre Hospitalier Universitaire (CHU) Grenoble-Alpes, Grenoble, France., Cantero F; R&D and Clinical Departments, PDC*line Pharma Belgique, Liège, Belgium., Chaperot L; Université Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Institute for Advanced Biosciences (IAB), team Translational Immunology and Immunotherapy in Chronic Disease, Grenoble, France.; Recherche et Développement, Etablissement Français du Sang Auvergne-Rhône-Alpes, Grenoble, France., Saas P; Université Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Institute for Advanced Biosciences (IAB), team Translational Immunology and Immunotherapy in Chronic Disease, Grenoble, France.; Recherche et Développement, Etablissement Français du Sang Auvergne-Rhône-Alpes, Grenoble, France., Skrzypski M; Department of Oncology and Radiotherapy, Medical University of Gdańsk, Gdańsk, Poland., Vansteenkiste J; Respiratory Oncology Unit (Pulmonology), University Hospitals Leuven, Leuven, Belgium., Plumas J; R&D Department, PDC*line Pharma France, Grenoble, France.; R&D and Clinical Departments, PDC*line Pharma Belgique, Liège, Belgium.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 04; Vol. 17, pp. 1763434. Date of Electronic Publication: 2026 Mar 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1763434