Directed evolution of a serine protease LsPLAase in Bacillus subtilis for high-yield secretory production and efficient depolymerization of polylactic acid.
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| Title: | Directed evolution of a serine protease LsPLAase in Bacillus subtilis for high-yield secretory production and efficient depolymerization of polylactic acid. |
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| Authors: | Cheng XT; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: nole7807@njtech.edu.cn., Wu L; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: 202361118049@njtech.edu.cn., Wang W; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: 1209796033@qq.com., Wu T; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: wutinghaohaoxuexi@126.com., Xie B; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: bksxb@njtech.edu.cn., Yan X; Key Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China. Electronic address: yanxin@njau.edu.cn., Dong W; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: dwl@njtech.edu.cn., Zhou J; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: jayzhou@njtech.edu.cn., Jiang M; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: bioengine@njtech.edu.cn. |
| Source: | Bioresource technology [Bioresour Technol] 2026 Jun; Vol. 450, pp. 134441. Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41861863 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Directed evolution of a serine protease LsPLAase in Bacillus subtilis for high-yield secretory production and efficient depolymerization of polylactic acid. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cheng+XT%22">Cheng XT</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: nole7807@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: 202361118049@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: 1209796033@qq.com.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: wutinghaohaoxuexi@126.com.<br /><searchLink fieldCode="AU" term="%22Xie+B%22">Xie B</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China. Electronic address: bksxb@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Key Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China. Electronic address: yanxin@njau.edu.cn.<br /><searchLink fieldCode="AU" term="%22Dong+W%22">Dong W</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: dwl@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: jayzhou@njtech.edu.cn.<br /><searchLink fieldCode="AU" term="%22Jiang+M%22">Jiang M</searchLink>; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China; Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, Nanjing Tech University, Nanjing 211816, Jiangsu, China. Electronic address: bioengine@njtech.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229889523%22">Bioresource technology</searchLink> [Bioresour Technol] 2026 Jun; Vol. 450, pp. 134441. <i>Date of Electronic Publication: </i>2026 Mar 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Applied+Science%22">Elsevier Applied Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9889523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2976 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608524%22">09608524 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Technol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41861863 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.biortech.2026.134441 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 134441 Titles: – TitleFull: Directed evolution of a serine protease LsPLAase in Bacillus subtilis for high-yield secretory production and efficient depolymerization of polylactic acid. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cheng XT – PersonEntity: Name: NameFull: Wu L – PersonEntity: Name: NameFull: Wang W – PersonEntity: Name: NameFull: Wu T – PersonEntity: Name: NameFull: Xie B – PersonEntity: Name: NameFull: Yan X – PersonEntity: Name: NameFull: Dong W – PersonEntity: Name: NameFull: Zhou J – PersonEntity: Name: NameFull: Jiang M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1873-2976 Numbering: – Type: volume Value: 450 Titles: – TitleFull: Bioresource technology Type: main |
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