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Biopreservation of a tissue engineered nigrostriatal pathway for tract reconstruction in Parkinson's disease.

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Title: Biopreservation of a tissue engineered nigrostriatal pathway for tract reconstruction in Parkinson's disease.
Authors: Chouhan D; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Browne KD; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Vélez WJG; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA., Karandikar SP; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA., Patel R; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Yankson KNA; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA., Shultz RB; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Duda JE; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cullen DK; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA. Electronic address: dkacy@pennmedicine.upenn.edu.
Source: Acta biomaterialia [Acta Biomater] 2026 May; Vol. 215, pp. 51-66. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Chouhan+D%22">Chouhan D</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Browne+KD%22">Browne KD</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vélez+WJG%22">Vélez WJG</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA.<br /><searchLink fieldCode="AU" term="%22Karandikar+SP%22">Karandikar SP</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA.<br /><searchLink fieldCode="AU" term="%22Patel+R%22">Patel R</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Yankson+KNA%22">Yankson KNA</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA.<br /><searchLink fieldCode="AU" term="%22Shultz+RB%22">Shultz RB</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Duda+JE%22">Duda JE</searchLink>; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Cullen+DK%22">Cullen DK</searchLink>; Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Neurotrauma, Neurodegeneration & Restoration, Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA, USA. Electronic address: dkacy@pennmedicine.upenn.edu.
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        Value: 10.1016/j.actbio.2026.03.031
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        Text: English
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              Text: 2026 May
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