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Structural basis for prostaglandin and drug transport via SLCO2A1.

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Title: Structural basis for prostaglandin and drug transport via SLCO2A1.
Authors: Joshi C; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK., Deme JC; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Nakamura Y; Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.; Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan., Hsu WT; Department of Biochemistry, University of Oxford, Oxford, UK.; Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, UK., Goult JD; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK., Kato T; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK., Parker JL; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK., Biggin PC; Department of Biochemistry, University of Oxford, Oxford, UK. Philip.biggin@bioch.ox.ac.uk.; Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, UK. Philip.biggin@bioch.ox.ac.uk., Lea SM; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA. susan.lea@stjude.org.; Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA. susan.lea@stjude.org., Nakanishi T; Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan. nakanishi@takasaki-u.ac.jp., Newstead S; Department of Biochemistry, University of Oxford, Oxford, UK. simon.newstead@bioch.ox.ac.uk.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK. simon.newstead@bioch.ox.ac.uk.
Source: Nature communications [Nat Commun] 2026 Mar 20; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural basis for prostaglandin and drug transport via SLCO2A1.
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  Data: <searchLink fieldCode="AU" term="%22Joshi+C%22">Joshi C</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Deme+JC%22">Deme JC</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nakamura+Y%22">Nakamura Y</searchLink>; Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.; Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.<br /><searchLink fieldCode="AU" term="%22Hsu+WT%22">Hsu WT</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.; Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Goult+JD%22">Goult JD</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kato+T%22">Kato T</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Parker+JL%22">Parker JL</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Biggin+PC%22">Biggin PC</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK. Philip.biggin@bioch.ox.ac.uk.; Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, UK. Philip.biggin@bioch.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lea+SM%22">Lea SM</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA. susan.lea@stjude.org.; Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA. susan.lea@stjude.org.<br /><searchLink fieldCode="AU" term="%22Nakanishi+T%22">Nakanishi T</searchLink>; Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan. nakanishi@takasaki-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Newstead+S%22">Newstead S</searchLink>; Department of Biochemistry, University of Oxford, Oxford, UK. simon.newstead@bioch.ox.ac.uk.; Kavli Institute of Nanoscience Discovery, University of Oxford, Oxford, UK. simon.newstead@bioch.ox.ac.uk.
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              Text: 2026 Mar 20
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