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Rectal nanoparticulate-hydrogel delivering budesonide to reduce enterohepatic drug metabolism and clearance.

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Title: Rectal nanoparticulate-hydrogel delivering budesonide to reduce enterohepatic drug metabolism and clearance.
Authors: Zhang RX; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China. zhangruixue@must.edu.mo.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China. zhangruixue@must.edu.mo.; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China. zhangruixue@must.edu.mo., Lu W; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Yan X; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Deng X; School of Life Sciences, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Wan R; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Song Z; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China., Liang J; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China., Wang XT; School of Life Sciences, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Cao T; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China., Chen Y; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China., Tam PKH; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China. pkhtam@must.edu.mo.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China. pkhtam@must.edu.mo.
Source: Drug delivery and translational research [Drug Deliv Transl Res] 2026 Mar 20. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rectal nanoparticulate-hydrogel delivering budesonide to reduce enterohepatic drug metabolism and clearance.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+RX%22">Zhang RX</searchLink>; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China. zhangruixue@must.edu.mo.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China. zhangruixue@must.edu.mo.; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China. zhangruixue@must.edu.mo.<br /><searchLink fieldCode="AU" term="%22Lu+W%22">Lu W</searchLink>; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; School of Life Sciences, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Wan+R%22">Wan R</searchLink>; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Song+Z%22">Song Z</searchLink>; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China.<br /><searchLink fieldCode="AU" term="%22Liang+J%22">Liang J</searchLink>; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China.<br /><searchLink fieldCode="AU" term="%22Wang+XT%22">Wang XT</searchLink>; School of Life Sciences, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Cao+T%22">Cao T</searchLink>; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China.<br /><searchLink fieldCode="AU" term="%22Tam+PKH%22">Tam PKH</searchLink>; Precision Regenerative Medicine Research Centre, Medical Sciences Division, Macau University of Science and Technology, Macau, China. pkhtam@must.edu.mo.; Faculty of Medicine, and School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China. pkhtam@must.edu.mo.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101540061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2190-3948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222190393X%22">2190393X </searchLink><i>NLM ISO Abbreviation: </i>Drug Deliv Transl Res <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s13346-026-02095-9
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              Text: 2026 Mar 20
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