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CD4+ T cells in Type 1 Diabetes: Inferring Stage-specific Dysregulation from scRNA-seq.

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Title: CD4+ T cells in Type 1 Diabetes: Inferring Stage-specific Dysregulation from scRNA-seq.
Authors: Tychinin DI; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Petriaikina ES; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Antonova OA; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Bogdanov VP; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia., Antysheva ZG; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia., Kaluzhskiy IN; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia., Avsievich ES; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia.; Moscow Clinical Scientific and Practical Center named after A.S. Loginov, Moscow 111123, Russia., Shchekina VS; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia.; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia., Krupinova JA; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia.; Moscow Clinical Scientific and Practical Center named after A.S. Loginov, Moscow 111123, Russia., Frolova TM; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia., Glushkova OV; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Vladimirov IS; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Mukhin VE; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Snigir EA; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Makhotenko AV; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Marchenko OM; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Ivashechkin AA; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Fateev OD; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Akimov VE; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Mitrofanov SI; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Grammatikati KS; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Nekrasova AI; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Gorev VV; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia., Valieva SI; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia., Rybkina IG; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia., Osmanov IM; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia., Kolomina IG; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia., Bukin SS; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia., Khatkov IE; Moscow Clinical Scientific and Practical Center named after A.S. Loginov, Moscow 111123, Russia., Bodunova NA; Moscow Clinical Scientific and Practical Center named after A.S. Loginov, Moscow 111123, Russia., Yudin VS; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Keskinov AA; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Yudin SM; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Yu Volchkov P; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia.; Moscow Clinical Scientific and Practical Center named after A.S. Loginov, Moscow 111123, Russia., Svetlichnyy DV; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia., Woroncow M; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia., Skvortsova VI; The Federal Medical Biological Agency (FMBA of Russia), Moscow 123182, Russia.
Source: Genomics, proteomics & bioinformatics [Genomics Proteomics Bioinformatics] 2026 Mar 21. Date of Electronic Publication: 2026 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press on behalf of Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation and Genetics Society of China Country of Publication: England NLM ID: 101197608 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-3244 (Electronic) Linking ISSN: 16720229 NLM ISO Abbreviation: Genomics Proteomics Bioinformatics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CD4+ T cells in Type 1 Diabetes: Inferring Stage-specific Dysregulation from scRNA-seq.
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Loginov, Moscow 111123, Russia.<br /><searchLink fieldCode="AU" term="%22Frolova+TM%22">Frolova TM</searchLink>; Moscow Center for Advanced Studies, Moscow 123592, Russia.; Federal State Budgetary Scientific Institution 'Federal Research Center for innovator and emerging biomedical and pharmaceutical technologies', Moscow 125315, Russia.<br /><searchLink fieldCode="AU" term="%22Glushkova+OV%22">Glushkova OV</searchLink>; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia.<br /><searchLink fieldCode="AU" term="%22Vladimirov+IS%22">Vladimirov IS</searchLink>; Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia.<br /><searchLink fieldCode="AU" term="%22Mukhin+VE%22">Mukhin VE</searchLink>; 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Federal State Budgetary Institution «Centre for Strategic Planning and Management of Biomedical Health Risks» of the Federal medical and biological agency (Centre for Strategic Planning, of the Federal medical and biological agency), Moscow 119121, Russia.<br /><searchLink fieldCode="AU" term="%22Gorev+VV%22">Gorev VV</searchLink>; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia.<br /><searchLink fieldCode="AU" term="%22Valieva+SI%22">Valieva SI</searchLink>; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia.<br /><searchLink fieldCode="AU" term="%22Rybkina+IG%22">Rybkina IG</searchLink>; Morozovskaya Children's City Clinical Hospital, Moscow 119049, Russia.<br /><searchLink fieldCode="AU" term="%22Osmanov+IM%22">Osmanov IM</searchLink>; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia.<br /><searchLink fieldCode="AU" term="%22Kolomina+IG%22">Kolomina IG</searchLink>; Bashliaeva Children's Municipal Clinical Hospital of the Moscow City Health Department, Moscow 125373, Russia.<br /><searchLink fieldCode="AU" term="%22Bukin+SS%22">Bukin SS</searchLink>; 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