Relevance of the diffusion tensor imaging along the perivascular space (DTI-ALPS) index in small vessel disease - A study in patients with mild ischaemic stroke.

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Title: Relevance of the diffusion tensor imaging along the perivascular space (DTI-ALPS) index in small vessel disease - A study in patients with mild ischaemic stroke.
Authors: Alvim DM; College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK., Valdés Hernández MDC; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Bastin ME; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK., Clancy U; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Arteaga-Reyes C; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Wiseman S; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Jochems ACC; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Garcia DJ; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Hamilton OKL; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; Health Economics and Health Technology Assessment, School of Health and Wellbeing, University of Glasgow, UK., Backhouse EV; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Cheng Y; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China., Thrippleton MJ; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Stringer MS; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Chappell FM; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Doubal FN; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK., Muñoz Maniega S; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK. Electronic address: s.m.maniega@ed.ac.uk., Wardlaw JM; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.
Source: Neurobiology of aging [Neurobiol Aging] 2026 Jul; Vol. 163, pp. 35-45. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE
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  Data: Relevance of the diffusion tensor imaging along the perivascular space (DTI-ALPS) index in small vessel disease - A study in patients with mild ischaemic stroke.
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  Data: <searchLink fieldCode="AU" term="%22Alvim+DM%22">Alvim DM</searchLink>; College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Valdés+Hernández+MDC%22">Valdés Hernández MDC</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Bastin+ME%22">Bastin ME</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Clancy+U%22">Clancy U</searchLink>; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Arteaga-Reyes+C%22">Arteaga-Reyes C</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Wiseman+S%22">Wiseman S</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Jochems+ACC%22">Jochems ACC</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Garcia+DJ%22">Garcia DJ</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hamilton+OKL%22">Hamilton OKL</searchLink>; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; Health Economics and Health Technology Assessment, School of Health and Wellbeing, University of Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Backhouse+EV%22">Backhouse EV</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Thrippleton+MJ%22">Thrippleton MJ</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Stringer+MS%22">Stringer MS</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Chappell+FM%22">Chappell FM</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Doubal+FN%22">Doubal FN</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Muñoz+Maniega+S%22">Muñoz Maniega S</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK. Electronic address: s.m.maniega@ed.ac.uk.<br /><searchLink fieldCode="AU" term="%22Wardlaw+JM%22">Wardlaw JM</searchLink>; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, UK; Row Fogo Centre for Research into Ageing and The Brain, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute Centre, and BHF-UK DRI Centre for Vascular Dementia Research, at the University of Edinburgh, UK.
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  Data: <searchLink fieldCode="JN" term="%228100437%22">Neurobiology of aging</searchLink> [Neurobiol Aging] 2026 Jul; Vol. 163, pp. 35-45. <i>Date of Electronic Publication: </i>2026 Mar 19.
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