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HNF4α-HKDC1 axis orchestrates a metabolic rewiring to promote migration and metastasis in advanced gastric cancer.

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Title: HNF4α-HKDC1 axis orchestrates a metabolic rewiring to promote migration and metastasis in advanced gastric cancer.
Authors: Xu X; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.; Department of Geriatrics, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wu H; Department of Gastroenterology, School of Medicine, Xiamen University, Xiamen, China.; Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China., Shang J; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Wang Y; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Yang Y; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Cai T; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Chen L; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Xu X; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Zhang C; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Zhang W; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China., Wang D; College of Clinical Medicine, Fujian Provincial Hospital, Fuzhou, China. daxuanwang@163.com., Zhang M; Department of Gastroenterology, School of Medicine, Xiamen University, Xiamen, China. zmqing8084@sina.com.; Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China. zmqing8084@sina.com., Zhan YY; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China. yyzhan@xmu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 23; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HNF4α-HKDC1 axis orchestrates a metabolic rewiring to promote migration and metastasis in advanced gastric cancer.
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  Data: <searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.; Department of Geriatrics, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Department of Gastroenterology, School of Medicine, Xiamen University, Xiamen, China.; Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China.<br /><searchLink fieldCode="AU" term="%22Shang+J%22">Shang J</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Cai+T%22">Cai T</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; College of Clinical Medicine, Fujian Provincial Hospital, Fuzhou, China. daxuanwang@163.com.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Department of Gastroenterology, School of Medicine, Xiamen University, Xiamen, China. zmqing8084@sina.com.; Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China. zmqing8084@sina.com.<br /><searchLink fieldCode="AU" term="%22Zhan+YY%22">Zhan YY</searchLink>; Cancer Research Center, School of Medicine, Xiamen University, Xiamen, China. yyzhan@xmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Mar 23; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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