Microbial signatures and host immune responses associated with the development of ventilator-associated pneumonia among patients with neurological injuries.

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Title: Microbial signatures and host immune responses associated with the development of ventilator-associated pneumonia among patients with neurological injuries.
Authors: Mancabelli L; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy., Palomba E; Department of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy., Magni F; NeuroIntensive Care Unit, Department Neuroscience, IRCCS Fondazione San Gerardo dei Tintori, Monza, Italy., Chatenoud L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Olgiati I; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Buracchi C; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Bugarin C; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Gaipa G; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Abbruzzese C; Department of Anaesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Filippini M; Department of Anesthesia, Intensive Care and Emergency, ASST Spedali Civili University Hospital, Brescia, Italy., Forastieri A; Département Anesthésie Réanimation, Hospitalier Universitaire (CHU) Saint-Etienne, Saint-Étienne, France., Fumagalli R; Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.; Department of Anesthesia and Intensive Care Medicine, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Geraldini F; Sant'Antonio Anesthesia and Intensive Care Unit, University-Hospital of Padua, Padua, Italy., Picetti E; Department of Anaesthesia and Intensive Care, Parma University Hospital, Parma, Italy., Terranova L; Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Vaschetto R; Department of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Italy., Zoerle T; Neuroscience Intensive Care Unit, Department of Anaesthesia and Critical Care, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Ventura M; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy.; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy., Citerio G; NeuroIntensive Care Unit, Department Neuroscience, IRCCS Fondazione San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Gori A; Department of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy.; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, Milan, Italy., Bandera A; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Alagna L; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Turroni F; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy.; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Source: Microbiology spectrum [Microbiol Spectr] 2026 Mar 23, pp. e0319325. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
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  Data: Microbial signatures and host immune responses associated with the development of ventilator-associated pneumonia among patients with neurological injuries.
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  Data: <searchLink fieldCode="AU" term="%22Mancabelli+L%22">Mancabelli L</searchLink>; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Palomba+E%22">Palomba E</searchLink>; Department of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Magni+F%22">Magni F</searchLink>; NeuroIntensive Care Unit, Department Neuroscience, IRCCS Fondazione San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Chatenoud+L%22">Chatenoud L</searchLink>; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Olgiati+I%22">Olgiati I</searchLink>; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Buracchi+C%22">Buracchi C</searchLink>; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Bugarin+C%22">Bugarin C</searchLink>; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Gaipa+G%22">Gaipa G</searchLink>; Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Abbruzzese+C%22">Abbruzzese C</searchLink>; Department of Anaesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Filippini+M%22">Filippini M</searchLink>; Department of Anesthesia, Intensive Care and Emergency, ASST Spedali Civili University Hospital, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Forastieri+A%22">Forastieri A</searchLink>; Département Anesthésie Réanimation, Hospitalier Universitaire (CHU) Saint-Etienne, Saint-Étienne, France.<br /><searchLink fieldCode="AU" term="%22Fumagalli+R%22">Fumagalli R</searchLink>; Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.; Department of Anesthesia and Intensive Care Medicine, Grande Ospedale Metropolitano Niguarda, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Geraldini+F%22">Geraldini F</searchLink>; Sant'Antonio Anesthesia and Intensive Care Unit, University-Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Picetti+E%22">Picetti E</searchLink>; Department of Anaesthesia and Intensive Care, Parma University Hospital, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Terranova+L%22">Terranova L</searchLink>; Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vaschetto+R%22">Vaschetto R</searchLink>; Department of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Zoerle+T%22">Zoerle T</searchLink>; Neuroscience Intensive Care Unit, Department of Anaesthesia and Critical Care, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ventura+M%22">Ventura M</searchLink>; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy.; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Citerio+G%22">Citerio G</searchLink>; NeuroIntensive Care Unit, Department Neuroscience, IRCCS Fondazione San Gerardo dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gori+A%22">Gori A</searchLink>; Department of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy.; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bandera+A%22">Bandera A</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Alagna+L%22">Alagna L</searchLink>; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Turroni+F%22">Turroni F</searchLink>; Interdepartmental Research Centre 'Microbiome Research Hub', University of Parma, Parma, Italy.; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
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