The Randomized Phase II ARC-9 Study of Etrumadenant-Based Therapy versus Regorafenib in Patients with Previously Treated Metastatic Colorectal Cancer.

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Title: The Randomized Phase II ARC-9 Study of Etrumadenant-Based Therapy versus Regorafenib in Patients with Previously Treated Metastatic Colorectal Cancer.
Authors: Cecchini M; Department of Internal Medicine, Medical Oncology, Yale University School of Medicine, New Haven, Connecticut., Han SW; Department of Internal Medicine, Seoul National University Hospital and Seoul National University Cancer Research Institute, Seoul, South Korea., Lee S; Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea., Lee KW; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea., Kopetz S; Division of Cancer Medicine, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mizrahi J; Department of Medical Oncology, Ochsner Medical Center, New Orleans, Louisiana., Hong YS; Department of Oncology, Asan Medical Center, Seoul, South Korea., Ghiringhelli F; Department of Medical Oncology, Centre Georges Francois Leclerc, Dijon, France., Italiano A; Department of Medicine, Institut Bergonie, Bordeaux, France.; Faculty of Medicine, University of Bordeaux, Bordeaux, France., Tougeron D; Department of Gastroenterology, Centre Hospitalier Universitaire de Poitiers, Poitiers, France., Beagle B; Arcus Biosciences, Inc., Hayward, California., Boakye M; Arcus Biosciences, Inc., Hayward, California., Zhao T; Arcus Biosciences, Inc., Hayward, California., Khemka V; Arcus Biosciences, Inc., Hayward, California., Wainberg ZA; Department of Gastrointestinal Medical Oncology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Jul 01; Vol. 32 (13), pp. 2593-2603.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Randomized Phase II ARC-9 Study of Etrumadenant-Based Therapy versus Regorafenib in Patients with Previously Treated Metastatic Colorectal Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Cecchini+M%22">Cecchini M</searchLink>; Department of Internal Medicine, Medical Oncology, Yale University School of Medicine, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Han+SW%22">Han SW</searchLink>; Department of Internal Medicine, Seoul National University Hospital and Seoul National University Cancer Research Institute, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KW%22">Lee KW</searchLink>; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.<br /><searchLink fieldCode="AU" term="%22Kopetz+S%22">Kopetz S</searchLink>; Division of Cancer Medicine, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Mizrahi+J%22">Mizrahi J</searchLink>; Department of Medical Oncology, Ochsner Medical Center, New Orleans, Louisiana.<br /><searchLink fieldCode="AU" term="%22Hong+YS%22">Hong YS</searchLink>; Department of Oncology, Asan Medical Center, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Ghiringhelli+F%22">Ghiringhelli F</searchLink>; Department of Medical Oncology, Centre Georges Francois Leclerc, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Italiano+A%22">Italiano A</searchLink>; Department of Medicine, Institut Bergonie, Bordeaux, France.; Faculty of Medicine, University of Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Tougeron+D%22">Tougeron D</searchLink>; Department of Gastroenterology, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Beagle+B%22">Beagle B</searchLink>; Arcus Biosciences, Inc., Hayward, California.<br /><searchLink fieldCode="AU" term="%22Boakye+M%22">Boakye M</searchLink>; Arcus Biosciences, Inc., Hayward, California.<br /><searchLink fieldCode="AU" term="%22Zhao+T%22">Zhao T</searchLink>; Arcus Biosciences, Inc., Hayward, California.<br /><searchLink fieldCode="AU" term="%22Khemka+V%22">Khemka V</searchLink>; Arcus Biosciences, Inc., Hayward, California.<br /><searchLink fieldCode="AU" term="%22Wainberg+ZA%22">Wainberg ZA</searchLink>; Department of Gastrointestinal Medical Oncology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2026 Jul 01; Vol. 32 (13), pp. 2593-2603.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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