Ibogalogs Activate the 5-HT2A Receptor through a Mechanism Involving Outward and Inward Movements of the Respective Transmembrane Segment TM6 and TM7.

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Title: Ibogalogs Activate the 5-HT2A Receptor through a Mechanism Involving Outward and Inward Movements of the Respective Transmembrane Segment TM6 and TM7.
Authors: Rudin D; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Division of Clinical Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Ren X; College of Life Science, Beijing Normal University, Beijing, China.; National Institute of Biological Sciences, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China., Liechti ME; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Division of Clinical Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Huang N; National Institute of Biological Sciences, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China.; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China., Arias HR; Department of Pharmacology and Physiology, College of Osteopathic Medicine, Oklahoma State University Center for Health Sciences, Tahlequah, OK, USA. hugo.arias@okstate.edu.
Source: Neurochemical research [Neurochem Res] 2026 Mar 23; Vol. 51 (2). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ibogalogs Activate the 5-HT<subscript>2A</subscript> Receptor through a Mechanism Involving Outward and Inward Movements of the Respective Transmembrane Segment TM6 and TM7.
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  Data: <searchLink fieldCode="AU" term="%22Rudin+D%22">Rudin D</searchLink>; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Division of Clinical Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ren+X%22">Ren X</searchLink>; College of Life Science, Beijing Normal University, Beijing, China.; National Institute of Biological Sciences, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liechti+ME%22">Liechti ME</searchLink>; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Division of Clinical Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Huang+N%22">Huang N</searchLink>; National Institute of Biological Sciences, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China.; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Arias+HR%22">Arias HR</searchLink>; Department of Pharmacology and Physiology, College of Osteopathic Medicine, Oklahoma State University Center for Health Sciences, Tahlequah, OK, USA. hugo.arias@okstate.edu.
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  Data: <searchLink fieldCode="JN" term="%227613461%22">Neurochemical research</searchLink> [Neurochem Res] 2026 Mar 23; Vol. 51 (2). <i>Date of Electronic Publication: </i>2026 Mar 23.
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        Value: 10.1007/s11064-026-04727-5
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      – Code: eng
        Text: English
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      – TitleFull: Ibogalogs Activate the 5-HT2A Receptor through a Mechanism Involving Outward and Inward Movements of the Respective Transmembrane Segment TM6 and TM7.
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            NameFull: Rudin D
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            NameFull: Ren X
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            NameFull: Huang N
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              Text: 2026 Mar 23
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