Sphingosine-1-phosphate promotes CD8 T cell exhaustion in breast cancer via exosomal transfer of TGFBR2.

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Title: Sphingosine-1-phosphate promotes CD8 T cell exhaustion in breast cancer via exosomal transfer of TGFBR2.
Authors: Bhoumick A; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India., Ghosh A; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India., Singh A; Abramson Cancer Center and Department of Medicine, University of Pennsylvania, Philadelphia, USA., Mandal S; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India., Agarwal T; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India., Halder R; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India., Das B; Netaji Subhas Chandra Bose Cancer Hospital, Nayabad, Kolkata, India., Mukhopadhyay S; Netaji Subhas Chandra Bose Cancer Hospital, Nayabad, Kolkata, India., Sen P; School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata, India. bcps@iacs.res.in.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 23; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08523-5