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Retraction Note: Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.

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Title: Retraction Note: Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.
Authors: Li Q; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, USA. qiuxia-li@uiowa.edu., Zhang Q; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, USA., Kim YR; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Gaddam RR; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Jacobs JS; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Bachschmid MM; Boston University School of Medicine, Boston, MA, USA., Younis T; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Zhu Z; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Veterans Affairs Medical Center, Iowa City, IA, USA., Zingman L; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Veterans Affairs Medical Center, Iowa City, IA, USA., London B; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Rauckhorst AJ; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Taylor EB; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Norris AW; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolic Phenotyping Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Vikram A; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Irani K; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Veterans Affairs Medical Center, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.
Source: Nature communications [Nat Commun] 2026 Mar 23; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article; Retraction Notice
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; In Process
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  Data: Retraction Note: Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.
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  Data: <searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. qiuxia-li@uiowa.edu.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, USA. qiuxia-li@uiowa.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YR%22">Kim YR</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Gaddam+RR%22">Gaddam RR</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Jacobs+JS%22">Jacobs JS</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Bachschmid+MM%22">Bachschmid MM</searchLink>; Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Younis+T%22">Younis T</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Veterans Affairs Medical Center, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Zingman+L%22">Zingman L</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Veterans Affairs Medical Center, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22London+B%22">London B</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Rauckhorst+AJ%22">Rauckhorst AJ</searchLink>; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+EB%22">Taylor EB</searchLink>; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Norris+AW%22">Norris AW</searchLink>; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolic Phenotyping Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Vikram+A%22">Vikram A</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Irani+K%22">Irani K</searchLink>; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Veterans Affairs Medical Center, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com.
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