Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.

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Title: Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.
Authors: de Souza JG; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil., Gurgel GG; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil., Rodrigues FM; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil., Braga RAM; Postgraduate Program in Cardiology, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Soares RAM; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil., Lage LAPC; Discipline of Haematology and Hemotherapy of the Faculty of Medicine, University of São Paulo (FMUSP) and Medical Research Laboratory LIM31 of FMUSP, São Paulo, SP, Brazil., Soares IC; Pathology Laboratory of the Cancer Institute of the State of São Paulo - ICESP, São Paulo, SP, Brazil., Levy D; Lipids, Oxidation and Cell Biology Team, Laboratory of Immunology (LIM19), Heart Institute (InCor), Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo-HCFMUSP, Sao Paulo, Brazil., Damasceno NRT; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil. nagila@usp.br.; Postgraduate Program in Cardiology, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, São Paulo, Brazil. nagila@usp.br.
Source: Inflammation [Inflammation] 2026 Mar 23; Vol. 49 (1). Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.
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  Data: <searchLink fieldCode="AU" term="%22de+Souza+JG%22">de Souza JG</searchLink>; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Gurgel+GG%22">Gurgel GG</searchLink>; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+FM%22">Rodrigues FM</searchLink>; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Braga+RAM%22">Braga RAM</searchLink>; Postgraduate Program in Cardiology, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+RAM%22">Soares RAM</searchLink>; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Lage+LAPC%22">Lage LAPC</searchLink>; Discipline of Haematology and Hemotherapy of the Faculty of Medicine, University of São Paulo (FMUSP) and Medical Research Laboratory LIM31 of FMUSP, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+IC%22">Soares IC</searchLink>; Pathology Laboratory of the Cancer Institute of the State of São Paulo - ICESP, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Levy+D%22">Levy D</searchLink>; Lipids, Oxidation and Cell Biology Team, Laboratory of Immunology (LIM19), Heart Institute (InCor), Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo-HCFMUSP, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Damasceno+NRT%22">Damasceno NRT</searchLink>; Department of Nutrition, School of Public Health, University of São Paulo, Av. Dr. Arnaldo. 715, São Paulo, 01246-904, SP, Brazil. nagila@usp.br.; Postgraduate Program in Cardiology, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, São Paulo, Brazil. nagila@usp.br.
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  Data: <searchLink fieldCode="JN" term="%227600105%22">Inflammation</searchLink> [Inflammation] 2026 Mar 23; Vol. 49 (1). <i>Date of Electronic Publication: </i>2026 Mar 23.
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        Value: 10.1007/s10753-025-02367-5
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              Text: 2026 Mar 23
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