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SETD2 methyltransferase activity promotes correct transcription initiation and termination.

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Title: SETD2 methyltransferase activity promotes correct transcription initiation and termination.
Authors: Kopczyńska M; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland., Nakayama C; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.; Department of Medical Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan., Stępień A; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland., Ito S; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan., Imami K; Proteome Homeostasis Research Unit, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan., Gdula MR; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland., Nojima T; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. nojima.takayuki.058@m.kyushu-u.ac.jp.; School of Medicine, Yokohama City University, 236-0004, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, Japan. nojima.takayuki.058@m.kyushu-u.ac.jp., Kamieniarz-Gdula K; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland. kinga.kamieniarz-gdula@amu.edu.pl.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland. kinga.kamieniarz-gdula@amu.edu.pl.
Source: EMBO reports [EMBO Rep] 2026 May; Vol. 27 (9), pp. 2218-2242. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SETD2 methyltransferase activity promotes correct transcription initiation and termination.
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  Data: <searchLink fieldCode="AU" term="%22Kopczyńska+M%22">Kopczyńska M</searchLink>; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland.<br /><searchLink fieldCode="AU" term="%22Nakayama+C%22">Nakayama C</searchLink>; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.; Department of Medical Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Stępień+A%22">Stępień A</searchLink>; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland.<br /><searchLink fieldCode="AU" term="%22Ito+S%22">Ito S</searchLink>; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.<br /><searchLink fieldCode="AU" term="%22Imami+K%22">Imami K</searchLink>; Proteome Homeostasis Research Unit, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Gdula+MR%22">Gdula MR</searchLink>; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland.; Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland.<br /><searchLink fieldCode="AU" term="%22Nojima+T%22">Nojima T</searchLink>; Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. nojima.takayuki.058@m.kyushu-u.ac.jp.; School of Medicine, Yokohama City University, 236-0004, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, Japan. nojima.takayuki.058@m.kyushu-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kamieniarz-Gdula+K%22">Kamieniarz-Gdula K</searchLink>; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614, Poznan, Poland. kinga.kamieniarz-gdula@amu.edu.pl.; Department of Molecular and Cellular Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614, Poznan, Poland. kinga.kamieniarz-gdula@amu.edu.pl.
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              Text: 2026 May
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