An international, multicentre, interventional, randomised, assessor-blinded trial to MAXimise the METHotrexate therapy potential in patients with active rheumatoid arthritis (MethMax trial): study protocol for a randomised controlled trial.
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| Title: | An international, multicentre, interventional, randomised, assessor-blinded trial to MAXimise the METHotrexate therapy potential in patients with active rheumatoid arthritis (MethMax trial): study protocol for a randomised controlled trial. |
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| Authors: | Anderle K; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Sieghart D; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Durechova M; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Bonnay F; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Kerschbaumer A; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Chatzidionysiou K; Department of Medicine, Solna, Division of Rheumatology, Karolinska University Hospital at Karolinska Institutet, Stockholm, Sweden., Knevel R; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands., Pitzalis C; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Lillegraven S; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Haavardsholm EA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Kristianslund EK; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Codreanu C; Center for Rheumatic Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Popescu C; Center for Rheumatic Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Gremese E; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., de Geest S; Nursing Science, Department Public Health, Faculty of Medicine, University of Basel, Basel, BS, Switzerland., Kocher A; Nursing Science, Department Public Health, Faculty of Medicine, University of Basel, Basel, BS, Switzerland., Makri S; Patient Research Partner, EULAR, Nicosia, Cyprus., Aletaha D; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria., Lechner-Radner H; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Guertel 18-20, Vienna, A-1090, Austria. helga.lechner-radner@meduniwien.ac.at. |
| Corporate Authors: | SQUEEZE Consortium |
| Source: | Trials [Trials] 2026 Mar 23; Vol. 27 (1). Date of Electronic Publication: 2026 Mar 23. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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