Enhanced dynamic risk stratification of smoldering multiple myeloma.

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Title: Enhanced dynamic risk stratification of smoldering multiple myeloma.
Authors: Chabrun F; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Laboratory of Biochemistry and Molecular Biology, University Hospital of Angers, University of Angers, Angers, France., Schwartz DE; Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital Biostatistics, Somerville, MA, USA., Gentile S; Sapienza University of Rome, Rome, Italy., Mai EK; Heidelberg Myeloma Center, Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Medical Faculty Heidelberg, Heidelberg, Germany., Gupta TR; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Yale School of Medicine, New Haven, CT, USA., Perry J; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Cordas Dos Santos DM; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Hielscher T; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Werly A; Heidelberg Myeloma Center, Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Medical Faculty Heidelberg, Heidelberg, Germany., Schmidt SK; Heidelberg Myeloma Center, Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Medical Faculty Heidelberg, Heidelberg, Germany., Theodorakakou F; National and Kapodistrian University of Athens, Athens, Greece., Fotiou D; National and Kapodistrian University of Athens, Athens, Greece., Liacos CI; National and Kapodistrian University of Athens, Athens, Greece., Kanellias N; National and Kapodistrian University of Athens, Athens, Greece., Gisbert NC; Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA) CIBER-ONC number CB16/12/00369, Pamplona, Spain., Martin-Sanchez E; Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA) CIBER-ONC number CB16/12/00369, Pamplona, Spain., Termini R; Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA) CIBER-ONC number CB16/12/00369, Pamplona, Spain., Waldschmidt J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Chavda SJ; Department of Haematology, Cancer Institute, University College London, London, UK., Ainley L; Department of Haematology, Cancer Institute, University College London, London, UK., Da Vià MC; Hematology section, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., De Magistris C; Hematology section, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Pettine L; Hematology section, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Timonian MA; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Alberge JB; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Patel V; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Costello P; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Tobia C; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Phan S; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Lamb J; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Silverio MT; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Davis M; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., O'Donnell EK; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Marinac CR; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Nadeem O; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Bolli N; Hematology section, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Yong K; Department of Haematology, Cancer Institute, University College London, London, UK., Kortüm KM; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Einsele H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Mateos MV; Department of Hematology, University Hospital of Salamanca/IBSAL/CIC/CIBERONC, Salamanca, Spain., Kumar S; Department of Hematology, Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA., San-Miguel JF; Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA) CIBER-ONC number CB16/12/00369, Pamplona, Spain., Paiva B; Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA) CIBER-ONC number CB16/12/00369, Pamplona, Spain., Kastritis E; National and Kapodistrian University of Athens, Athens, Greece., Dimopoulos MA; National and Kapodistrian University of Athens, Athens, Greece.; Department of Medicine, Korea University, Seoul, South Korea., Raab MS; Heidelberg Myeloma Center, Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Medical Faculty Heidelberg, Heidelberg, Germany., Trippa L; Departement of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA. ltrippa@ds.dfci.harvard.edu., Ghobrial IM; Center for Early Detection and Interception-Blood Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. irene_ghobrial@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. irene_ghobrial@dfci.harvard.edu.
Source: Nature medicine [Nat Med] 2026 May; Vol. 32 (5), pp. 1745-1753. Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: Enhanced dynamic risk stratification of smoldering multiple myeloma.
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Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bolli+N%22">Bolli N</searchLink>; Hematology section, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Yong+K%22">Yong K</searchLink>; Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kortüm+KM%22">Kortüm KM</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Einsele+H%22">Einsele H</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mateos+MV%22">Mateos MV</searchLink>; Department of Hematology, University Hospital of Salamanca/IBSAL/CIC/CIBERONC, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; 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              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1546-170X
          Numbering:
            – Type: volume
              Value: 32
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Nature medicine
              Type: main
ResultId 1