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Metabolic changes in normal-appearing white matter associate with MRI measures of disease burden in relapsing-remitting multiple sclerosis over three years.

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Title: Metabolic changes in normal-appearing white matter associate with MRI measures of disease burden in relapsing-remitting multiple sclerosis over three years.
Authors: Zöchner A; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria., Bogner W; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria., Dal-Bianco A; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria., Strasser B; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria., Hangel G; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Department of Neurosurgery, Medical University of Vienna, Währinger Straße 18-20, 1090, Vienna, Austria., Rommer PS; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria., Niess E; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria. eva.niess@meduniwien.ac.at.
Source: Scientific reports [Sci Rep] 2026 Mar 24; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Metabolic changes in normal-appearing white matter associate with MRI measures of disease burden in relapsing-remitting multiple sclerosis over three years.
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  Data: <searchLink fieldCode="AU" term="%22Zöchner+A%22">Zöchner A</searchLink>; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bogner+W%22">Bogner W</searchLink>; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Dal-Bianco+A%22">Dal-Bianco A</searchLink>; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Strasser+B%22">Strasser B</searchLink>; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hangel+G%22">Hangel G</searchLink>; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria.; Department of Neurosurgery, Medical University of Vienna, Währinger Straße 18-20, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Rommer+PS%22">Rommer PS</searchLink>; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Niess+E%22">Niess E</searchLink>; High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Lazarettgasse 14, 1090, Vienna, Austria. eva.niess@meduniwien.ac.at.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Mar 24; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Mar 24.
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