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A fully implantable intraspinal microstimulation device for early preclinical evaluation of feasibility, stability, and functionality.

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Title: A fully implantable intraspinal microstimulation device for early preclinical evaluation of feasibility, stability, and functionality.
Authors: Mirkiani S; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada., O'Sullivan CL; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada., Arefadib A; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada., Tyreman N; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada., Sari K; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada., Wilson D; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada., Tawakol O; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, USA., Troyk PR; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, USA., Fox R; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Neurosurgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada., Mushahwar VK; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada. Vivian.Mushahwar@ualberta.ca.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada. Vivian.Mushahwar@ualberta.ca.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada. Vivian.Mushahwar@ualberta.ca.
Source: Scientific reports [Sci Rep] 2026 Mar 24; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Mirkiani+S%22">Mirkiani S</searchLink>; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22O'Sullivan+CL%22">O'Sullivan CL</searchLink>; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Arefadib+A%22">Arefadib A</searchLink>; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Tyreman+N%22">Tyreman N</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Sari+K%22">Sari K</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+D%22">Wilson D</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Tawakol+O%22">Tawakol O</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, USA.<br /><searchLink fieldCode="AU" term="%22Troyk+PR%22">Troyk PR</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, USA.<br /><searchLink fieldCode="AU" term="%22Fox+R%22">Fox R</searchLink>; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada.; Division of Neurosurgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Mushahwar+VK%22">Mushahwar VK</searchLink>; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada. Vivian.Mushahwar@ualberta.ca.; Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART), University of Alberta, Edmonton, Canada. Vivian.Mushahwar@ualberta.ca.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, AB, Canada. Vivian.Mushahwar@ualberta.ca.
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              Text: 2026 Mar 24
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