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Collagen-mediated pro-tumorigenic MAPK activation drives stromal-immune reprogramming in solid cancers.

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Title: Collagen-mediated pro-tumorigenic MAPK activation drives stromal-immune reprogramming in solid cancers.
Authors: Ding J; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China., Lin H; Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.; The First Clinical Medicine College, Nanjing Medical University, Nanjing, Jiangsu, China.; Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China., Fan H; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China., Xu L; Department of Gastroenterology, Sheyang County People's Hospital, Yancheng, Jiangsu, China., Zhou H; Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.; Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, China., Jiang H; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China., Wang Z; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China., Xia T; Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China., Cai Y; Central Laboratory, Jintan Affiliated Hospital of Jiangsu University, Changzhou, Jiangsu, China., Zhu Y; Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China.; Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China., Xu J; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 24; Vol. 17, pp. 1744126. Date of Electronic Publication: 2026 Feb 24 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Collagen-mediated pro-tumorigenic MAPK activation drives stromal-immune reprogramming in solid cancers.
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  Data: <searchLink fieldCode="AU" term="%22Ding+J%22">Ding J</searchLink>; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.; The First Clinical Medicine College, Nanjing Medical University, Nanjing, Jiangsu, China.; Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Fan+H%22">Fan H</searchLink>; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Department of Gastroenterology, Sheyang County People's Hospital, Yancheng, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.; Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Xia+T%22">Xia T</searchLink>; Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Cai+Y%22">Cai Y</searchLink>; Central Laboratory, Jintan Affiliated Hospital of Jiangsu University, Changzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China.; Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 24
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