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Pathological phimosis is associated with foreskin immune cell infiltration but not microbiota composition.

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Title: Pathological phimosis is associated with foreskin immune cell infiltration but not microbiota composition.
Authors: Penney R; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada., Buchanan LB; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Rojas-Vargas J; Department of Biology, Western University, London, Ontario, Canada., Lin J; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Khan Y; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Davidson J; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada., Wilson CA; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada., Tai V; Department of Biology, Western University, London, Ontario, Canada., Russo TA; Feinberg School of Medicine, Cell and Developmental Biology Department, Northwestern University, Chicago, Illinois, USA., Hope TJ; Feinberg School of Medicine, Cell and Developmental Biology Department, Northwestern University, Chicago, Illinois, USA., Wilcox H; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Monari B; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA., Ravel J; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA., Al KF; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada., Dave S; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada., Wang PZT; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada., Burton JP; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada., Prodger JL; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Source: MSphere [mSphere] 2026 Apr 28; Vol. 11 (4), pp. e0072525. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE
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  Data: Pathological phimosis is associated with foreskin immune cell infiltration but not microbiota composition.
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  Data: <searchLink fieldCode="AU" term="%22Penney+R%22">Penney R</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Buchanan+LB%22">Buchanan LB</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Rojas-Vargas+J%22">Rojas-Vargas J</searchLink>; Department of Biology, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Khan+Y%22">Khan Y</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Davidson+J%22">Davidson J</searchLink>; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+CA%22">Wilson CA</searchLink>; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tai+V%22">Tai V</searchLink>; Department of Biology, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Russo+TA%22">Russo TA</searchLink>; Feinberg School of Medicine, Cell and Developmental Biology Department, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Hope+TJ%22">Hope TJ</searchLink>; Feinberg School of Medicine, Cell and Developmental Biology Department, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Wilcox+H%22">Wilcox H</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Monari+B%22">Monari B</searchLink>; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Ravel+J%22">Ravel J</searchLink>; Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Al+KF%22">Al KF</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Dave+S%22">Dave S</searchLink>; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+PZT%22">Wang PZT</searchLink>; Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burton+JP%22">Burton JP</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Centre for Human Microbiome and Probiotic Research, Lawson Research Institute, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Prodger+JL%22">Prodger JL</searchLink>; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101674533%22">MSphere</searchLink> [mSphere] 2026 Apr 28; Vol. 11 (4), pp. e0072525. <i>Date of Electronic Publication: </i>2026 Mar 25.
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